Area of research
Molecular Biology · Oncology
Research interest
Research interests include Cancer-related Molecular Pathways, Cell death mechanisms and regulation, DNA Repair Mechanisms, and Retinoids in leukemia and cellular processes.
The p21CIP1-CDK4-DREAM axis is a master regulator of genotoxic stress-induced cellular senescence
Puzzling phenomenon: adult-onset cancer predisposition and pediatric cancer
Novel hydroxamic acid derivative induces apoptosis and constrains autophagy in leukemic cells
Simultaneous <i>Nbs1</i> and <i>p53</i> inactivation in neural progenitors triggers high‐grade gliomas
Class I HDAC overexpression promotes temozolomide resistance in glioma cells by regulating RAD18 expression
p53 triggers mitochondrial apoptosis following DNA damage-dependent replication stress by the hepatotoxin methyleugenol
Cyclin B/CDK1 and Cyclin A/CDK2 phosphorylate DENR to promote mitotic protein translation and faithful cell division
Regulating the p53 Tumor Suppressor Network at PML Biomolecular Condensates
Multi-layered chromatin proteomics identifies cell vulnerabilities in DNA repair
The Role of p53 Signaling in Colorectal Cancer
Ferroptosis Meets Cell–Cell Contacts
The gut microbiota instructs the hepatic endothelial cell transcriptome
DAZAP2 acts as specifier of the p53 response to DNA damage
Multi-layered chromatin proteomics identifies cell vulnerabilities in DNA repair
Pancreatic Ductal Adenocarcinoma (PDAC) Organoids: The Shining Light at the End of the Tunnel for Drug Response Prediction and Personalized Medicine
Benzo[a]pyrene represses DNA repair through altered E2F1/E2F4 function marking an early event in DNA damage-induced cellular senescence
Vpu modulates DNA repair to suppress innate sensing and hyper-integration of HIV-1
ATRIP protects progenitor cells against DNA damage in vivo
Progenitor death drives retinal dysplasia and neuronal degeneration in a mouse model of ATRIP-Seckel syndrome
Correction: ATRIP protects progenitor cells against DNA damage in vivo
Cell Fate Regulation upon DNA Damage: p53 Serine 46 Kinases Pave the Cell Death Road
Identification of responders to immune checkpoint therapy: which biomarkers have the highest value?
The SIAH1–HIPK2–p53ser46 Damage Response Pathway is Involved in Temozolomide-Induced Glioblastoma Cell Death
Methylation profiling identifies two subclasses of squamous cell carcinoma related to distinct cells of origin
Abstract 5333: Methylation profiling identifies two subclasses of cutaneous squamous cell carcinoma related to distinct cell types of origin
Effects of the Mammalian Target of Rapamycin Inhibitor Everolimus on Hepatitis C Virus Replication In Vitro and In Vivo
The DNA damage-induced cell death response: a roadmap to kill cancer cells
Tumor Suppressor Genes within Common Fragile Sites Are Active Players in the DNA Damage Response
A Thymic Epithelial Stem Cell Pool Persists throughout Ontogeny and Is Modulated by TGF-β
HIPK2 restricts SIRT1 activity upon severe DNA damage by a phosphorylation-controlled mechanism