← back to search

Bart Spee

Utrecht University · NL
Area of research
Hepatology · Biomedical Engineering
Research interest
Research interests include Organoid, Biology, Cell biology, Cholangiocyte, Progenitor cell, and Pathology.
h-index
citations
3,609
works
43
NIH funding
primary concept
email

Recent publications

Gelatin-Based Hybrid Hydrogels as Matrices for Organoid Culture
Biomacromolecules 2024cited by 28position: middledoi
Chemically Defined Organoid Culture System for Cholangiocyte Differentiation
Advanced Healthcare Materials 2024cited by 11position: lastdoi
Accelerated production of human epithelial organoids in a miniaturized spinning bioreactor
Cell Reports Methods 2024cited by 10position: middledoi
The application of organ-on-chip models for the prediction of human pharmacokinetic profiles during drug development
Pharmacological Research 2023cited by 39position: middledoi
Drug Metabolism of Hepatocyte-like Organoids and Their Applicability in In Vitro Toxicity Testing
Molecules 2023cited by 27position: lastdoi
Volumetric Bioprinting of Organoids and Optically Tuned Hydrogels to Build Liver‐Like Metabolic Biofactories
Advanced Materials 2022cited by 245position: middledoi
Hydrogels derived from decellularized liver tissue support the growth and differentiation of cholangiocyte organoids
Biomaterials 2022cited by 101position: middledoi
A human kidney and liver organoid‐based multi‐organ‐on‐a‐chip model to study the therapeutic effects and biodistribution of mesenchymal stromal cell‐derived extracellular vesicles
Journal of Extracellular Vesicles 2022cited by 93position: middledoi
Human Cholangiocytes Form a Polarized and Functional Bile Duct on Hollow Fiber Membranes
Frontiers in Bioengineering and Biotechnology 2022cited by 26position: lastdoi
Hepatic bile acid synthesis and secretion: Comparison of in vitro methods
Toxicology Letters 2022cited by 23position: middledoi
Bioprinting of Human Liver‐Derived Epithelial Organoids for Toxicity Studies
Macromolecular Bioscience 2021cited by 42position: lastdoi
The potential and limitations of intrahepatic cholangiocyte organoids to study inborn errors of metabolism
Journal of Inherited Metabolic Disease 2021cited by 14position: middledoi
A Chemically Defined Hydrogel for Human Liver Organoid Culture
Advanced Functional Materials 2020cited by 160position: middledoi
Cellulose Nanofibril Hydrogel Promotes Hepatic Differentiation of Human Liver Organoids
Advanced Healthcare Materials 2020cited by 90position: lastdoi
Human extrahepatic and intrahepatic cholangiocyte organoids show region-specific differentiation potential and model cystic fibrosis-related bile duct disease
Scientific Reports 2020cited by 86position: middledoi
Generation of Differentiating and Long-Living Intestinal Organoids Reflecting the Cellular Diversity of Canine Intestine
Cells 2020cited by 56position: middledoi
Long-Term Survival of Transplanted Autologous Canine Liver Organoids in a COMMD1-Deficient Dog Model of Metabolic Liver Disease
Cells 2020cited by 54position: lastdoi
Hepatitis E virus seroprevalence in pets in the Netherlands and the permissiveness of canine liver cells to the infection
Irish Veterinary Journal 2020cited by 23position: middledoi
Tissue-Engineered Bile Ducts for Disease Modeling and Therapy
Tissue Engineering Part C Methods 2020cited by 22position: lastdoi
Large‐Scale Production of LGR5‐Positive Bipotential Human Liver Stem Cells
Hepatology 2019cited by 138position: lastdoi
Hydrogels for Liver Tissue Engineering
Bioengineering 2019cited by 107position: middledoi
A Versatile Biosynthetic Hydrogel Platform for Engineering of Tissue Analogues
Advanced Healthcare Materials 2019cited by 92position: middledoi
Characterization of Endothelial and Smooth Muscle Cells From Different Canine Vessels
Frontiers in Physiology 2019cited by 29position: middledoi
Intestinal Failure and Aberrant Lipid Metabolism in Patients With DGAT1 Deficiency
Gastroenterology 2018cited by 122position: middledoi
Biotechnology Challenges to In Vitro Maturation of Hepatic Stem Cells
Gastroenterology 2018cited by 107position: lastdoi
Bioengineered bile ducts recapitulate key cholangiocyte functions
Biofabrication 2018cited by 47position: lastdoi
Hepatocyte‐like cells generated by direct reprogramming from murine somatic cells can repopulate decellularized livers
Biotechnology and Bioengineering 2018cited by 21position: lastdoi
Long-Term Adult Feline Liver Organoid Cultures for Disease Modeling of Hepatic Steatosis
Stem Cell Reports 2017cited by 110position: lastdoi
Converging biofabrication and organoid technologies: the next frontier in hepatic and intestinal tissue engineering?
Biofabrication 2017cited by 105position: middledoi
Sensitivity and Specificity of Plasma ALT, ALP, and Bile Acids for Hepatitis in Labrador Retrievers
Journal of Veterinary Internal Medicine 2017cited by 44position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Louis C. Penning · Utrecht University17 papers (2012–2022)Luc J. W. van der Laan · University of Padua15 papers (2016–2024)Kerstin Schneeberger · Utrecht University13 papers (2017–2024)Monique E. van Wolferen · Utrecht University11 papers (2014–2022)Loes A. Oosterhoff · Utrecht University10 papers (2015–2021)Jan Rothuizen · Utrecht University8 papers (2012–2020) · 7 papers (2012–2017)Hedwig S. Kruitwagen · Utrecht University7 papers (2014–2020)Hans Clevers · Oncode Institute7 papers (2015–2020)Shicheng Ye · Utrecht University7 papers (2019–2024)Frank G. van Steenbeek · Utrecht University7 papers (2013–2023)Hille Fieten · Utrecht University6 papers (2012–2020)Niels Geijsen · Leiden University Medical Center6 papers (2015–2020)Guy C. M. Grinwis · Utrecht University6 papers (2013–2020)Monique M.A. Verstegen · Rotterdam University of Applied Sciences5 papers (2017–2024)Rosalinde Masereeuw · Utrecht University5 papers (2018–2024)Jos Malda · University of Applied Sciences Utrecht5 papers (2017–2024)Baukje A. Schotanus · Utrecht University5 papers (2012–2020)Sabine A. Fuchs · Utrecht University4 papers (2019–2024)Chen Chen · Utrecht University4 papers (2015–2018)