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Guy C. M. Grinwis

Utrecht University · NL
Area of research
Pulmonary and Respiratory Medicine · Small Animals
Research interest
Research focused on Intervertebral disc and Degeneration (medical), with related work in Organoid, Lumbosacral joint, TLR7. Notable publications include 'Intervertebral disc degeneration in the dog. Part 2: Chondrodystrophic and non-chondrodystrophic breeds', 'Intervertebral disc degeneration in the dog. Part 1: Anatomy and physiology of the intervertebral disc and characteristics of intervertebral disc degeneration', and 'Disease Modeling and Gene Therapy of Copper Storage Disease in Canine Hepatic Organoids'.
h-index
citations
1,905
works
34
NIH funding
primary concept
email

Recent publications

Mycobacterium bovis infected domestic cats in an officially bovine tuberculosis free country resulting in human infection
One Health 2025cited by 6position: middledoi
Reference intervals for plasma, urinary, and salivary concentrations of free metanephrines in dogs: Relevance to the diagnosis of pheochromocytoma
Journal of Veterinary Internal Medicine 2023cited by 17position: middledoi
Vaccination against Extracellular Vimentin for Treatment of Urothelial Cancer of the Bladder in Client-Owned Dogs
Cancers 2023cited by 12position: middledoi
Laparoscopic vs. open adrenalectomy: perioperative data and survival analysis in 70 dogs with an adrenal tumor
Frontiers in Veterinary Science 2023cited by 11position: middledoi
Genetic Basis of Dilated Cardiomyopathy in Dogs and Its Potential as a Bidirectional Model
Animals 2022cited by 20position: middledoi
Multi-omics approach identifies germline regulatory variants associated with hematopoietic malignancies in retriever dog breeds
PLoS Genetics 2021cited by 24position: middledoi
Long-Term Survival of Transplanted Autologous Canine Liver Organoids in a COMMD1-Deficient Dog Model of Metabolic Liver Disease
Cells 2020cited by 54position: middledoi
Controlled release of celecoxib inhibits inflammation, bone cysts and osteophyte formation in a preclinical model of osteoarthritis
Drug Delivery 2018cited by 53position: middledoi
Intervertebral Disc Degeneration in Warmblood Horses: Morphology, Grading, and Distribution of Lesions
Veterinary Pathology 2018cited by 42position: lastdoi
Pathological Findings in the Pituitary Glands of Dogs and Cats
Veterinary Pathology 2018cited by 28position: middledoi
Chronic iron overload causing haemochromatosis and hepatopathy in 21 horses and one donkey
Equine Veterinary Journal 2018cited by 27position: middledoi
Long-Term Adult Feline Liver Organoid Cultures for Disease Modeling of Hepatic Steatosis
Stem Cell Reports 2017cited by 110position: middledoi
Intradiscal application of a PCLA–PEG–PCLA hydrogel loaded with celecoxib for the treatment of back pain in canines: What's in it for humans?
Journal of Tissue Engineering and Regenerative Medicine 2017cited by 50position: middledoi
White muscle disease in foals: focus on selenium soil content. A case series
BMC Veterinary Research 2017cited by 44position: lastdoi
The Myth of Fibroid Degeneration in the Canine Intervertebral Disc: A Histopathological Comparison of Intervertebral Disc Degeneration in Chondrodystrophic and Nonchondrodystrophic Dogs
Veterinary Pathology 2017cited by 42position: lastdoi
Inflammatory profiles in canine intervertebral disc degeneration
BMC Veterinary Research 2016cited by 62position: middledoi
Disease Modeling and Gene Therapy of Copper Storage Disease in Canine Hepatic Organoids
Stem Cell Reports 2015cited by 115position: middledoi
A novel injectable thermoresponsive and cytocompatible gel of poly(N-isopropylacrylamide) with layered double hydroxides facilitates siRNA delivery into chondrocytes in 3D culture
Acta Biomaterialia 2015cited by 55position: middledoi
Intradiscal application of rhBMP-7 does not induce regeneration in a canine model of spontaneous intervertebral disc degeneration
Arthritis Research & Therapy 2015cited by 54position: middledoi
Biocompatibility and intradiscal application of a thermoreversible celecoxib-loaded poly-N-isopropylacrylamide MgFe-layered double hydroxide hydrogel in a canine model
Arthritis Research & Therapy 2015cited by 53position: middledoi
Estimated incidence rate and distribution of tumours in 4,653 cases of archival submissions derived from the Dutch golden retriever population
BMC Veterinary Research 2014cited by 39position: middledoi
Hydrated nucleus pulposus herniation in seven dogs
The Veterinary Journal 2014cited by 27position: middledoi
The canine hepatic progenitor cell niche: Molecular characterisation in health and disease
The Veterinary Journal 2014cited by 15position: middledoi
Gene expression profiling of early intervertebral disc degeneration reveals a down-regulation of canonical Wnt signaling and caveolin-1 expression: implications for development of regenerative strategies
Arthritis Research & Therapy 2013cited by 77position: middledoi
Safety and efficacy field study of artesunate for dogs with non-resectable tumours.
PubMed 2013cited by 49position: middle
Increased Osmolarity and Cell Clustering Preserve Canine Notochordal Cell Phenotype in Culture
Tissue Engineering Part C Methods 2013cited by 48position: middledoi
Gene Expression Profiling of Histiocytic Sarcomas in a Canine Model: The Predisposed Flatcoated Retriever Dog
PLoS ONE 2013cited by 31position: middledoi
Aberrant Gene Expression in Dogs with Portosystemic Shunts
PLoS ONE 2013cited by 27position: middledoi
Intervertebral disc degeneration in the dog. Part 2: Chondrodystrophic and non-chondrodystrophic breeds
The Veterinary Journal 2012cited by 201position: middledoi
Intervertebral disc degeneration in the dog. Part 1: Anatomy and physiology of the intervertebral disc and characteristics of intervertebral disc degeneration
The Veterinary Journal 2012cited by 170position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Björn P. Meij · Utrecht University14 papers (2012–2018)Marianna A. Tryfonidou · Utrecht University11 papers (2012–2018)Niklas Bergknut · Utrecht University10 papers (2012–2018)Laura B. Creemers · Utrecht University8 papers (2012–2018)Louis C. Penning · Utrecht University7 papers (2013–2020)Lucas A. Smolders · Utrecht University7 papers (2012–2017)Bart Spee · Utrecht University6 papers (2013–2020)Herman A.W. Hazewinkel · Utrecht University5 papers (2012–2013)Nicole Willems · Utrecht University5 papers (2015–2017)Jan Rothuizen · Utrecht University4 papers (2014–2020)Gerard R. Rutteman · Altrecht GGZ4 papers (2013–2021)Frank G. van Steenbeek · Utrecht University4 papers (2013–2022)Monique E. van Wolferen · Utrecht University4 papers (2013–2020)Hedwig S. Kruitwagen · Utrecht University4 papers (2014–2020)Anna R. Tellegen · Utrecht University4 papers (2015–2018)Saskia Plomp · Utrecht University3 papers (2015–2017)Jeannette Wolfswinkel · Utrecht University3 papers (2015–2020)Baukje A. Schotanus · Utrecht University3 papers (2015–2020) · 3 papers (2012–2012)Loes A. Oosterhoff · Utrecht University3 papers (2015–2020)