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Thomas Moore

Kent Hospital ·
Area of research
Neurology · Urology
Research interest
Research interests include Vascular Malformations Diagnosis and Treatment, Intracerebral and Subarachnoid Hemorrhage Research, Intracranial Aneurysms: Treatment and Complications, and Urological Disorders and Treatments.
h-index
34
citations
3,710
works
187
NIH funding
primary concept
email

Recent publications

Transcriptomic signatures of individual cell types in cerebral cavernous malformation
Cell Communication and Signaling 2024cited by 10position: middledoi
mTORC1 Inhibitor Rapamycin Inhibits Growth of Cerebral Cavernous Malformation in Adult Mice
Stroke 2023cited by 21position: middledoi
Plasma metabolites with mechanistic and clinical links to the neurovascular disease cavernous angioma
Communications Medicine 2023cited by 14position: middledoi
Circulating Plasma miRNA Homologs in Mice and Humans Reflect Familial Cerebral Cavernous Malformation Disease
Translational Stroke Research 2022cited by 4position: middledoi
PIK3CA and CCM mutations fuel cavernomas through a cancer-like mechanism
Nature 2021cited by 188position: middledoi
Astrocytes propel neurovascular dysfunction during cerebral cavernous malformation lesion formation
Journal of Clinical Investigation 2021cited by 59position: middledoi
Abortive intussusceptive angiogenesis causes multi-cavernous vascular malformations
eLife 2021cited by 23position: middledoi
Perfusion and Permeability<scp>MRI</scp>Predicts Future Cavernous Angioma Hemorrhage and Growth
Journal of Magnetic Resonance Imaging 2021cited by 14position: middledoi
Novel Murine Models of Cerebral Cavernous Malformations
Angiogenesis 2020cited by 51position: middledoi
Cerebral cavernous malformations are driven by ADAMTS5 proteolysis of versican
The Journal of Experimental Medicine 2020cited by 47position: middledoi
Propranolol inhibits cavernous vascular malformations by β1 adrenergic receptor antagonism in animal models
Journal of Clinical Investigation 2020cited by 43position: middledoi
A Roadmap for Developing Plasma Diagnostic and Prognostic Biomarkers of Cerebral Cavernous Angioma With Symptomatic Hemorrhage (CASH)
Neurosurgery 2020cited by 30position: middledoi
Antibodies in cerebral cavernous malformations react with cytoskeleton autoantigens in the lesional milieu
Journal of Autoimmunity 2020cited by 11position: middledoi
Distinct cellular roles for PDCD10 define a gut-brain axis in cerebral cavernous malformation
Science Translational Medicine 2019cited by 72position: middledoi
Rho Kinase Inhibition Blunts Lesion Development and Hemorrhage in Murine Models of Aggressive <i>Pdcd10/Ccm3</i> Disease
Stroke 2019cited by 57position: middledoi
Comprehensive transcriptome analysis of cerebral cavernous malformation across multiple species and genotypes
JCI Insight 2019cited by 56position: middledoi
Biomarkers of cavernous angioma with symptomatic hemorrhage
JCI Insight 2019cited by 46position: middledoi
Transcriptome clarifies mechanisms of lesion genesis versus progression in models of Ccm3 cerebral cavernous malformations
Acta Neuropathologica Communications 2019cited by 46position: middledoi
A Brain-Targeted Orally Available ROCK2 Inhibitor Benefits Mild and Aggressive Cavernous Angioma Disease
Translational Stroke Research 2019cited by 38position: middledoi
Plasma Biomarkers of Inflammation and Angiogenesis Predict Cerebral Cavernous Malformation Symptomatic Hemorrhage or Lesional Growth
Circulation Research 2018cited by 73position: middledoi
Phenotypic characterization of murine models of cerebral cavernous malformations
Laboratory Investigation 2018cited by 26position: middledoi
Endothelial TLR4 and the microbiome drive cerebral cavernous malformations
Nature 2017cited by 298position: middledoi
Thrombospondin1 (TSP1) replacement prevents cerebral cavernous malformations
The Journal of Experimental Medicine 2017cited by 101position: middledoi
B-Cell Depletion Reduces the Maturation of Cerebral Cavernous Malformations in Murine Models
Journal of Neuroimmune Pharmacology 2016cited by 54position: middledoi
Micro-computed tomography in murine models of cerebral cavernous malformations as a paradigm for brain disease
Journal of Neuroscience Methods 2016cited by 40position: middledoi

Grants

RUI: Adding Spin to a Gravitational Wave Detector Simulator
NSF2012127$145,2232020–2024PIRePORTER
SBIR Phase II: Optical Delivery System for In Situ Heating and Excitation in the Transmission Electron Microscope
NSF1853201$1,085,8252019–2023PIRePORTER
SBIR Phase I: Optical Delivery System for In Situ Heating and Excitation in the Transmission Electron Microscope
NSF1746019$224,9692018–2018PIRePORTER
RUI: Undergraduate Research in Musical Acoustics
NSF1607049$371,6452016–2020PIRePORTER
RUI: Undergraduate Research in Musical Acoustics
NSF1303251$214,7452013–2016PIRePORTER
SBIR Phase II: Photon Enhanced SEM (Scanning Electron Microscopes) Platform for Nano-Manufacturing
NSF0956765$448,0012010–2013PIRePORTER
RUI: Undergraduate Research in Musical Acoustics
NSF0964783$178,7872010–2013PIRePORTER
SBIR Phase I: Photon Enhanced SEM Platform for Nano-Manufacturing
NSF0839497$100,0002009–2009PIRePORTER
RUI: High Speed Electronic Speckle Pattern Interferometer for Undergraduate Research in Musical Acoustics
NSF0551310$154,5572007–2010PIRePORTER
SBIR Phase I: An Issue Development, Exploration and Analysis System (IDEA) to Support Group-Based Environmental Decision-Making for Brownfields Redevelopment
NSF9760360$75,6251998–1998PIRePORTER
Membrane Lipid Biosynthesis in Chlamydomonas Reinhardtii
NSF9603626$208,0001997–2000PIRePORTER
Engineering Techniques for Modeling Left Ventricular Energetics During Regional Myocardial Dysfunctions: Effectsof Cardiac Assistance
NSF9022060$195,5951991–1996PIRePORTER
Phosphatidylcholine Synthesis in Plants
NSF9003817$215,0001990–1993PIRePORTER
A Facility for Biophysical, Biochemical and Molecular Genetic Studies of Photosynthesis
NSF8804992$604,5491988–1991PIRePORTER
Regulation of Phosphatidylcholine Synthesis in Plants
NSF8703739$221,4921987–1990PIRePORTER
U.S.-France Cooperative Science: Biomimetic Transmembrane Charge Separation
NSF8514252$16,4591986–1988PIRePORTER
Regulation of Phosphatidylcholine Synthesis in Plants
NSF8402001$201,1191984–1987PIRePORTER
Multi-User Sound Laboratory Equipment Replacement
NSF8315346$58,0001984–1986PIRePORTER
Ultrastructure, Biochemistry, and Phylogeny of the Trentepohliaceae
NSF8308420$65,6331983–1986PIRePORTER
Phospholipids and Mitochondrial Biogenesis
NSF8300519$56,6151982–1984PIRePORTER
Phospholipids and Mitochondrial Biogenesis
NSF8025006$90,0001981–1982PIRePORTER
Energies of Metastable Excited States of Biomolecules Determined By Photoacoustic Spectroscopy. the Lowest Excited Triplet Energy of Carotenoid Polyenes
NSF8021718$62,8791981–1983PIRePORTER
Phospholipid Metabolism in Castor Bean Endosperm
NSF7611933$134,9001976–1981PIRePORTER

Frequent collaborators

Issam A. Awad · University of Chicago17 papers (2016–2024)Robert Shenkar · University of Chicago16 papers (2016–2024)Rhonda Lightle · University of Chicago16 papers (2016–2024)Romuald Girard · Txcell (France)15 papers (2016–2024)Douglas A. Marchuk · University of Virginia10 papers (2016–2024)Ying Cao · Nanjing Agricultural University10 papers (2016–2020)Mark H. Ginsberg · Mahindra and Mahindra Limited (India)7 papers (2017–2024) · 7 papers (2016–2020)Janne Koskimäki · Oulu University Hospital7 papers (2018–2024)Nicholas Hobson · McMaster University7 papers (2019–2021)Changbin Shi · Harbin Medical University7 papers (2016–2024)Hussein A. Zeineddine · The University of Texas Health Science Center6 papers (2016–2019)Mark L. Kahn · California University of Pennsylvania5 papers (2016–2024)Sharbel Romanos · University of Chicago5 papers (2019–2024)Agnieszka Stadnik · University of Chicago5 papers (2018–2024)Miguel Alejandro Lopez‐Ramirez · University of California San Diego5 papers (2017–2024)Le Shen · University of Illinois Chicago4 papers (2016–2020)Abhinav Srinath · University of Chicago4 papers (2020–2024)Sean P. Polster · University of Illinois Chicago4 papers (2018–2019)Maged D Fam · Oasis Hospital4 papers (2016–2018)