Area of research
Molecular Biology
Research interest
Research interests include RNA Research and Splicing, RNA modifications and cancer, Genomics and Chromatin Dynamics, and RNA and protein synthesis mechanisms.
irCLIP-RNP and Re-CLIP reveal patterns of dynamic protein assemblies on RNA
The adhesion GPCR ADGRL2 engages Gα13 to enable epidermal differentiation
Spatially resolved clonal copy number alterations in benign and malignant tissue
Integrating single-cell and spatial transcriptomics to elucidate intercellular tissue dynamics
Super-resolved spatial transcriptomics by deep data fusion
Multimodal Analysis of Composition and Spatial Architecture in Human Squamous Cell Carcinoma
Structural modularity of the XIST ribonucleoprotein complex
Spen links RNA-mediated endogenous retrovirus silencing and X chromosome inactivation
The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2
HiChIRP reveals RNA-associated chromosome conformation
Coupled Single-Cell CRISPR Screening and Epigenomic Profiling Reveals Causal Gene Regulatory Networks
Transcript-indexed ATAC-seq for precision immune profiling
Retinoic acid and BMP4 cooperate with p63 to alter chromatin dynamics during surface epithelial commitment
Cancer-Associated Long Noncoding RNA SMRT-2 Controls Epidermal Differentiation
1435 Dynamic morphogen-p63 chromatin interactions that guide epigenetic changes and p63 activity in surface ectoderm commitment
182 Single-cell RNA-sequencing reveals SCC intratumoral heterogeneity
An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues
The functions and unique features of long intergenic non-coding RNA
Enhancer connectome in primary human cells identifies target genes of disease-associated DNA elements
Lineage-specific dynamic and pre-established enhancer–promoter contacts cooperate in terminal differentiation
CSNK1a1 Regulates PRMT1 to Maintain the Progenitor State in Self-Renewing Somatic Tissue
519 Phase I/IIa clinical trial for recessive dystrophic epidermolysis bullosa using genetically corrected autologous keratinocytes
464 Dynamic and stable enhancer-promoter contacts regulate epidermal terminal differentiation
408 Discovery of differential RNA binding and regulation by the APOL4 protein to disease-linked psoriasis CDSN gene variants using RaPID
117 K-RAS oncogene activation is regulated by a snoRNA/SNARE protein axis that controls its subcellular transport
121 The SNORD86 small non-coding RNA binds and regulates Rac1
811 Attenuated netrin-1 receptor mediated regulation of tiam1 is required for rac1 mutant melanoma progression
123 RNA-protein interaction detection (RaPID) in living cells uncovers post-transcriptional regulation in carcinogenesis
HiChIP: efficient and sensitive analysis of protein-directed genome architecture
A LncRNA-MAF:MAFB Transcription Factor Network Regulates Epidermal Differentiation