Area of research
Molecular Biology · Hematology
Research interest
Research interests include Acute Myeloid Leukemia Research, CRISPR and Genetic Engineering, Autophagy in Disease and Therapy, and Single-cell and spatial transcriptomics.
Inherited resilience to clonal hematopoiesis by modifying stem cell RNA regulation
Somatic deficiency of the human E3 ubiquitin ligase CBL in leukocytes impairs B cell but not T cell development and function
Transcription factor networks disproportionately enrich for heritability of blood cell phenotypes
CEBPA repression by MECOM blocks differentiation to drive aggressive leukemias
Deciphering cell states and genealogies of human haematopoiesis
A noncoding regulatory variant in IKZF1 increases acute lymphoblastic leukemia risk in Hispanic/Latino children
Massively parallel base editing to map variant effects in human hematopoiesis
A genetic disorder reveals a hematopoietic stem cell regulatory network co-opted in leukemia
Drug discovery for Diamond-Blackfan anemia using reprogrammed hematopoietic progenitors
Progress towards generation of human haematopoietic stem cells
Congenital disorders of autophagy: an emerging novel class of inborn errors of neuro-metabolism
Protein degradation pathways in Parkinson’s disease: curse or blessing