Area of research
Molecular Biology · Surgery
Research interest
Research interests include Cholesterol and Lipid Metabolism, Drug Transport and Resistance Mechanisms, Estrogen and related hormone effects, and Retinoids in leukemia and cellular processes.
FGF21 counteracts alcohol intoxication by activating the noradrenergic nervous system
Glucocorticoid mediated inhibition of LKB1 mutant non-small cell lung cancers
The energy balance model of obesity: beyond calories in, calories out
The ‘nuclear option’ revisited: Confirmation of Ss-daf-12 function and therapeutic potential in Strongyloides stercoralis and other parasitic nematode infections
FGF21 promotes thermogenic gene expression as an autocrine factor in adipocytes
Characterization of the endogenous DAF-12 ligand and its use as an anthelmintic agent in Strongyloides stercoralis
The Schistosoma mansoni nuclear receptor FTZ-F1 maintains esophageal gland function via transcriptional regulation of meg-8.3
Pancreatitis is an FGF21-deficient state that is corrected by replacement therapy
Dafachronic acid and temperature regulate canonical dauer pathways during Nippostrongylus brasiliensis infectious larvae activation
A Dozen Years of Discovery: Insights into the Physiology and Pharmacology of FGF21
The Hormone FGF21 Stimulates Water Drinking in Response to Ketogenic Diet and Alcohol
PPARγ-K107 SUMOylation regulates insulin sensitivity but not adiposity in mice
FGF19, FGF21, and an FGFR1/β-Klotho-Activating Antibody Act on the Nervous System to Regulate Body Weight and Glycemia
FGF21 Is an Exocrine Pancreas Secretagogue
Methylprednisolone acetate induces, and Δ7-dafachronic acid suppresses,<i>Strongyloides stercoralis</i>hyperinfection in NSG mice
Nuclear receptors: emerging drug targets for parasitic diseases
Prolongevity hormone FGF21 protects against immune senescence by delaying age-related thymic involution
Regulation of Life Cycle Checkpoints and Developmental Activation of Infective Larvae in Strongyloides stercoralis by Dafachronic Acid
Impaired 17,20-Lyase Activity in Male Mice Lacking Cytochrome b5 in Leydig Cells
FGF21 Regulates Sweet and Alcohol Preference
Detection of FGF15 in Plasma by Stable Isotope Standards and Capture by Anti-peptide Antibodies and Targeted Mass Spectrometry
The Nuclear Receptor DAF-12 Regulates Nutrient Metabolism and Reproductive Growth in Nematodes
Loss of the liver X receptor LXRα/β in peripheral sensory neurons modifies energy expenditure
Nuclear Receptors, RXR, and the Big Bang
Circulating FGF21 Is Liver Derived and Enhances Glucose Uptake During Refeeding and Overfeeding
FGF21 Acts Centrally to Induce Sympathetic Nerve Activity, Energy Expenditure, and Weight Loss
Tissue-specific actions of the metabolic hormones FGF15/19 and FGF21
Glucocorticoids Regulate the Metabolic Hormone FGF21 in a Feed-Forward Loop
SnapShot: Hormones of the Gastrointestinal Tract
FGF21 regulates metabolism and circadian behavior by acting on the nervous system