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James B. Lok

California University of Pennsylvania · US
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Area of research
Parasitology · Ecology
Research interest
Research focused on Strongyloides stercoralis and Caenorhabditis elegans, with related work in Strongyloidiasis, Nuclear receptor, Cell biology. Notable publications include 'The genomic basis of parasitism in the Strongyloides clade of nematodes', 'Diverse Host-Seeking Behaviors of Skin-Penetrating Nematodes', and 'Regulation of Life Cycle Checkpoints and Developmental Activation of Infective Larvae in Strongyloides stercoralis by Dafachronic Acid'.
h-index
citations
624
works
8
NIH funding
primary concept
email

Recent publications

The ‘nuclear option’ revisited: Confirmation of Ss-daf-12 function and therapeutic potential in Strongyloides stercoralis and other parasitic nematode infections
Molecular and Biochemical Parasitology 2022cited by 5position: firstdoi
Characterization of the endogenous DAF-12 ligand and its use as an anthelmintic agent in Strongyloides stercoralis
eLife 2021cited by 18position: middledoi
Methylprednisolone acetate induces, and Δ7-dafachronic acid suppresses,<i>Strongyloides stercoralis</i>hyperinfection in NSG mice
Proceedings of the National Academy of Sciences 2017cited by 62position: middledoi
The genomic basis of parasitism in the Strongyloides clade of nematodes
Nature Genetics 2016cited by 278position: middledoi
Regulation of Life Cycle Checkpoints and Developmental Activation of Infective Larvae in Strongyloides stercoralis by Dafachronic Acid
PLoS Pathogens 2016cited by 80position: lastdoi
The Nuclear Receptor DAF-12 Regulates Nutrient Metabolism and Reproductive Growth in Nematodes
PLoS Genetics 2015cited by 51position: middledoi
Diverse Host-Seeking Behaviors of Skin-Penetrating Nematodes
PLoS Pathogens 2014cited by 94position: middledoi
Hc-daf-2 encodes an insulin-like receptor kinase in the barber’s pole worm, Haemonchus contortus, and restores partial dauer regulation
International Journal for Parasitology 2014cited by 36position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

David J. Mangelsdorf · Southwestern Medical Center5 papers (2015–2022)Steven A. Kliewer · Southwestern Medical Center5 papers (2015–2022)Zhu Wang · Ministry of Ecology and Environment4 papers (2015–2021) · 3 papers (2014–2017) · 2 papers (2015–2016)Mark L. Eberhard · University of Georgia1 papers (2017–2017)David Abraham · Thomas Jefferson University1 papers (2017–2017) · 1 papers (2021–2021)Min Hu · Nanchang University1 papers (2014–2014)Young‐Jai You · The University of Texas Southwestern Medical Center1 papers (2015–2015)Spencer S. Gang · University of California San Diego1 papers (2014–2014)John B. Patton · Thomas Jefferson University1 papers (2017–2017)Jet Tsien · Southwestern Medical Center1 papers (2021–2021)April Torigian · Thomas Jefferson University1 papers (2017–2017) · 1 papers (2014–2014)Rui Zhou · Xinyang College of Agriculture and Forestry1 papers (2014–2014)Jessica M. Deckman · University of Kentucky1 papers (2017–2017)Heping Deng · Southwestern Medical Center1 papers (2021–2021)Tian Qin · China National Pharmaceutical Group Corporation (China)1 papers (2021–2021)Mennatallah M. Y. Albarqi · University of Massachusetts Chan Medical School1 papers (2016–2016)
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