Area of research
Molecular Biology · Immunology
Research interest
Research interests include Cancer research, Biology, Gene knockdown, Small hairpin RNA, Downregulation and upregulation, and EZH2.
PDE7A inhibition suppresses triple-negative breast cancer by attenuating de novo pyrimidine biosynthesis
ALK inhibitors suppress HCC and synergize with anti-PD-1 therapy and ABT-263 in preclinical models
CBX5 loss drives EGFR inhibitor resistance and results in therapeutically actionable vulnerabilities in lung cancer
UBE2T promotes breast cancer tumor growth by suppressing DNA replication stress
EZH2 inhibits NK cell–mediated antitumor immunity by suppressing CXCL10 expression in an HDAC10-dependent manner
PSPH promotes melanoma growth and metastasis by metabolic deregulation-mediated transcriptional activation of NR4A1
Disruptor of telomeric silencing 1-like promotes ovarian cancer tumor growth by stimulating pro-tumorigenic metabolic pathways and blocking apoptosis
KLF7 promotes pancreatic cancer growth and metastasis by up-regulating ISG expression and maintaining Golgi complex integrity
Loss of HAT1 expression confers BRAFV600E inhibitor resistance to melanoma cells by activating MAPK signaling via IGF1R
Inhibition of Enhancer of zeste homolog 2 (EZH2) induces natural killer cell-mediated eradication of hepatocellular carcinoma cells