Area of research
Molecular Biology · Oncology
Research interest
Research interests include Cancer research, Biology, Immune system, Metastasis, Melanoma, and Gene knockdown.
Immune evasion in ovarian cancer: implications for immunotherapy and emerging treatments
NSD proteins in anti-tumor immunity and their therapeutic targeting by protein degraders
PDE7A inhibition suppresses triple-negative breast cancer by attenuating de novo pyrimidine biosynthesis
Roles and therapeutic targeting of ceramide metabolism in cancer
ALK inhibitors suppress HCC and synergize with anti-PD-1 therapy and ABT-263 in preclinical models
Combinatorial targeting of immune checkpoints and epigenetic regulators for hepatocellular carcinoma therapy
HOXC6 drives a therapeutically targetable pancreatic cancer growth and metastasis pathway by regulating MSK1 and PPP2R2B
CBX5 loss drives EGFR inhibitor resistance and results in therapeutically actionable vulnerabilities in lung cancer
Transcriptional determinants of cancer immunotherapy response and resistance
EZH2 inhibits NK cell–mediated antitumor immunity by suppressing CXCL10 expression in an HDAC10-dependent manner
PSPH promotes melanoma growth and metastasis by metabolic deregulation-mediated transcriptional activation of NR4A1
RNF2 ablation reprograms the tumor-immune microenvironment and stimulates durable NK and CD4+ T-cell-dependent antitumor immunity
N-acylsphingosine amidohydrolase 1 promotes melanoma growth and metastasis by suppressing peroxisome biogenesis-induced ROS production
PON2 subverts metabolic gatekeeper functions in B cells to promote leukemogenesis
KLF7 promotes pancreatic cancer growth and metastasis by up-regulating ISG expression and maintaining Golgi complex integrity
LIMK2 promotes the metastatic progression of triple-negative breast cancer by activating SRPK1
Transcriptional regulators and alterations that drive melanoma initiation and progression
Combining PARP and DNA-PK Inhibitors With Irradiation Inhibits HPV-Negative Head and Neck Cancer Squamous Carcinoma Growth
Loss of thymidine kinase 1 inhibits lung cancer growth and metastatic attributes by reducing GDF15 expression
Inhibition of Enhancer of zeste homolog 2 (EZH2) induces natural killer cell-mediated eradication of hepatocellular carcinoma cells
MELK Promotes Melanoma Growth by Stimulating the NF-κB Pathway
MARCH1 regulates insulin sensitivity by controlling cell surface insulin receptor levels
TRIM37 is a new histone H2A ubiquitin ligase and breast cancer oncoprotein
miR-146a promotes the initiation and progression of melanoma by activating Notch signaling
Genetic and pharmacological reactivation of the mammalian inactive X chromosome
Synergistic tumor suppression by combined inhibition of telomerase and CDKN1A
PEA15 Regulates the DNA Damage-Induced Cell Cycle Checkpoint and Oncogene-Directed Transformation
PTEN functions as a melanoma tumor suppressor by promoting host immune response
MEN1 Is a Melanoma Tumor Suppressor That Preserves Genomic Integrity by Stimulating Transcription of Genes That Promote Homologous Recombination-Directed DNA Repair
Genome-Wide RNAi Screening to Identify Regulators of Oncogene-Induced Cellular Senescence