Area of research
Molecular Biology · Materials Chemistry
Research interest
Research interests include Enzyme Structure and Function, Biochemical and Molecular Research, RNA and protein synthesis mechanisms, and Ion channel regulation and function.
Structural basis of prostaglandin efflux by MRP4
Structure and dynamics of the essential endogenous mycobacterial polyketide synthase Pks13
Destabilizers of the thymidylate synthase homodimer accelerate its proteasomal degradation and inhibit cancer growth
Author response: Destabilizers of the thymidylate synthase homodimer accelerate its proteasomal degradation and inhibit cancer growth
Highlighting membrane protein structure and function: A celebration of the Protein Data Bank
Structural basis for <i>Clostridium perfringens</i> enterotoxin targeting of claudins at tight junctions in mammalian gut
Key computational findings reveal proton transfer as driving the functional cycle in the phosphate transporter PiPT
Disrupters of the Thymidylate Synthase Homodimer Accelerate Its Proteasomal Degradation and Inhibit Cancer Growth.
Disrupters of the Thymidylate Synthase Homodimer Accelerate Its Proteasomal Degradation and Inhibit Cancer Growth.
A SARS-CoV-2 protein interaction map reveals targets for drug repurposing
Ion transport and regulation in a synaptic vesicle glutamate transporter
Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients
Ceapins block the unfolded protein response sensor ATF6α by inducing a neomorphic inter-organelle tether
Claudin-9 structures reveal mechanism for toxin-induced gut barrier breakdown
Structures suggest a mechanism for energy coupling by a family of organic anion transporters
Structural basis for activation of voltage sensor domains in an ion channel TPC1
Crystal structure and mechanistic basis of a functional homolog of the antigen transporter TAP
Mechanism of inhibition of human glucose transporter GLUT1 is conserved between cytochalasin B and phenylalanine amides
Structure, inhibition and regulation of two-pore channel TPC1 from Arabidopsis thaliana
Structure of Bor1 supports an elevator transport mechanism for SLC4 anion exchangers
Substrates Control Multimerization and Activation of the Multi-Domain ATPase Motor of Type VII Secretion
Fungal association and utilization of phosphate by plants: success, limitations, and future prospects
Crystal Structure of the Human tRNA m1A58 Methyltransferase–tRNA3Lys Complex: Refolding of Substrate tRNA Allows Access to the Methylation Target
Architecture of a single membrane spanning cytochrome P450 suggests constraints that orient the catalytic domain relative to a bilayer
Structure of sugar-bound LacY
Subnanometre-resolution electron cryomicroscopy structure of a heterodimeric ABC exporter
Crystal Structure of a Eukaryotic Phosphate Transporter
Structural basis for alternating access of a eukaryotic calcium/proton exchanger
Coordinating the impact of structural genomics on the human α-helical transmembrane proteome
Structures of intermediate transport states of ZneA, a Zn(II)/proton antiporter
MRIConsortium: Collaborative Development of Sample Delivery Instrument for Femtosecond Diffraction Studies
Protein Lipid & Protein Nucleic Acid Interactions
Protein-Lipid and Protein-Nucleic Acid Interactions
Protein-Lipid and Protein-Nucleic Acid Interactions
Protein-Lipid and Protein-Nucleic Acid Interactions
Sfc Travel Award (In Indian Currency) to Attend the International Symposium on Biomolecular Structure, Conformation, Function & Evolution, Madras, India, 01/4-7/78
Protein-Lipid and Protein-Nucleic Acid Interactions