Area of research
Molecular Biology · Biochemistry
Research interest
Research interests include Amino Acid Enzymes and Metabolism, Computational Drug Discovery Methods, Drug Transport and Resistance Mechanisms, and Protein Structure and Dynamics.
Expanding the utility of variant effect predictions with phenotype-specific models
Functional genomics of OCTN2 variants informs protein-specific variant effect predictor for Carnitine Transporter Deficiency
Describing inhibitor specificity for the amino acid transporter LAT1 from metainference simulations
PredictProtein - Predicting Protein Structure and Function for 29 Years
Human neurons from Christianson syndrome iPSCs reveal mutation-specific responses to rescue strategies
Maternal health around pregnancy and autism risk: a diagnosis-wide, population-based study
Artificial intelligence and machine learning‐aided drug discovery in central nervous system diseases: State‐of‐the‐arts and future directions
Maternal health around pregnancy and autism risk: a population-based study.
Reevaluating the Substrate Specificity of the L-Type Amino Acid Transporter (LAT1)
A whole-animal platform to advance a clinical kinase inhibitor into new disease space
Association of Autism Spectrum Disorder With Prenatal Exposure to Medication Affecting Neurotransmitter Systems
Human neurons from Christianson syndrome iPSCs reveal allele-specific responses to rescue strategies
Impaired Amino Acid Transport at the Blood Brain Barrier Is a Cause of Autism Spectrum Disorder
Mutations in the Na+/Citrate Cotransporter NaCT (SLC13A5) in Pediatric Patients with Epilepsy and Developmental Delay
Ligand Discovery for the Alanine-Serine-Cysteine Transporter (ASCT2, SLC1A5) from Homology Modeling and Virtual Screening
PredictProtein—an open resource for online prediction of protein structural and functional features
Loss-of-function variants of SETD5 cause intellectual disability and the core phenotype of microdeletion 3p25.3 syndrome
Structure-based ligand discovery for the Large-neutral Amino Acid Transporter 1, LAT-1
Crystal Structure of a Eukaryotic Phosphate Transporter
Evolution of modular intraflagellar transport from a coatomer-like progenitor
Structural basis for alternating access of a eukaryotic calcium/proton exchanger
Molecular Modeling and Ligand Docking for Solute Carrier (SLC) Transporters
SLC Classification: An Update
Coordinating the impact of structural genomics on the human α-helical transmembrane proteome