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Joseph D. Buxbaum

Child Health and Development Institute ·
Area of research
Genetics · Cognitive Neuroscience
Research interest
Research interests include Autism Spectrum Disorder Research, Genetics and Neurodevelopmental Disorders, Genomic variations and chromosomal abnormalities, and Alzheimer's disease research and treatments.
h-index
140
citations
118,292
works
783
NIH funding
primary concept
Medicine
email

Recent publications

Identifying Phelan-McDermid-Like Electrophysiological Subtypes in Autism Using EEG and Machine Learning
bioRxiv (Cold Spring Harbor Laboratory) 2026cited by 0position: middledoi
Familial confounding in the associations between maternal health and autism
Nature Medicine 2025cited by 23position: middledoi
Psychiatric genetics in the diverse landscape of Latin American populations
Nature Genetics 2025cited by 14position: middledoi
Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies known and novel cross-population and ancestry-specific associations as novel risk loci for Alzheimer’s disease
Genome biology 2025cited by 12position: middledoi
Protein-truncating variants and deletions of SHANK2 are associated with autism spectrum disorder and other neurodevelopmental concerns
Journal of Neurodevelopmental Disorders 2025cited by 3position: middledoi
Deleterious coding variation associated with autism is consistent across populations, as exemplified by admixed Latin American populations
medRxiv 2025cited by 3position: lastdoi
A framework to infer <i>de novo</i> exonic variants when parental genotypes are missing enhances association studies of autism
Bioinformatics 2025cited by 1position: middledoi
Familial Risk and Heritability of Lower Urinary Tract Symptoms in Children and Young Adults
medRxiv 2025cited by 0position: middledoi
Regulation of cell distancing in peri-plaque glial nets by Plexin-B1 affects glial activation and amyloid compaction in Alzheimer’s disease
Nature Neuroscience 2024cited by 35position: middledoi
Proximity analysis of native proteomes reveals phenotypic modifiers in a mouse model of autism and related neurodevelopmental conditions
Nature Communications 2024cited by 24position: middledoi
Clinical, genetic, and cognitive correlates of seizure occurrences in Phelan-McDermid syndrome
Journal of Neurodevelopmental Disorders 2024cited by 7position: middledoi
Identification of moderate effect size genes in autism spectrum disorder through a novel gene pairing approach
medRxiv 2024cited by 5position: middledoi
Expanding GABAergic Neuronal Diversity in PSC-Derived Disease Models
bioRxiv (Cold Spring Harbor Laboratory) 2024cited by 2position: middledoi
Skipping of Exon 20 in <i>EP300</i> : A Novel Variant Linked to Rubinstein–Taybi Syndrome With Atypical and Severe Clinical Manifestations
Clinical Genetics 2024cited by 1position: middledoi
Aortic Root Dilation and Genotype Associations in Phelan‐<scp>McDermid</scp> Syndrome
American Journal of Medical Genetics Part A 2024cited by 0position: middledoi
A significant role for maternal genetic nurture in the risk architecture of attention-deficit/hyperactivity disorder
medRxiv 2024cited by 0position: middledoi
Comorbidities in autism spectrum disorder and their etiologies
Translational Psychiatry 2023cited by 243position: middledoi
Associations of Sex, Race, and Apolipoprotein E Alleles With Multiple Domains of Cognition Among Older Adults
JAMA Neurology 2023cited by 53position: middledoi
Updated consensus guidelines on the management of Phelan–McDermid syndrome
American Journal of Medical Genetics Part A 2023cited by 47position: middledoi
Schizophrenia-associated somatic copy-number variants from 12,834 cases reveal recurrent NRXN1 and ABCB11 disruptions
Cell Genomics 2023cited by 43position: middledoi
The clinical and molecular spectrum of the KDM6B-related neurodevelopmental disorder
The American Journal of Human Genetics 2023cited by 30position: middledoi
Skewed X-chromosome inactivation in unsolved neurodevelopmental disease cases can guide re-evaluation For X-linked genes
European Journal of Human Genetics 2023cited by 23position: middledoi
An evolutionary perspective on complex neuropsychiatric disease
Neuron 2023cited by 20position: middledoi
Missense variants in RPH3A cause defects in excitatory synaptic function and are associated with a clinically variable neurodevelopmental disorder
Genetics in Medicine 2023cited by 16position: middledoi
Somatic comorbidities of mental disorders in pregnancy
European Psychiatry 2023cited by 5position: middledoi
Prospective phenotyping of CHAMP1 disorder indicates that coding mutations may not act through haploinsufficiency
Human Genetics 2023cited by 2position: lastdoi
Identification of shared and differentiating genetic architecture for autism spectrum disorder, attention-deficit hyperactivity disorder and case subgroups
Nature Genetics 2022cited by 74position: middledoi
Exome-wide association study to identify rare variants influencing COVID-19 outcomes: Results from the Host Genetics Initiative
PLoS Genetics 2022cited by 65position: middledoi
Statistical and functional convergence of common and rare genetic influences on autism at chromosome 16p
Nature Genetics 2022cited by 55position: middledoi
Population-level variation in enhancer expression identifies disease mechanisms in the human brain
Nature Genetics 2022cited by 52position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Alexander Kolevzon · Boston Children's Hospital34 papers (2012–2025)Silvia De Rubeis · Allen Institute for Brain Science27 papers (2013–2024)Paige M. Siper · University of Bristol24 papers (2015–2026)Abraham Reichenberg · New York State Office of Mental Health22 papers (2014–2025)Dorothy E. Grice · Mount Sinai Hospital19 papers (2014–2025)Sven Sandin · Karolinska Institutet18 papers (2014–2025)Danielle Halpern · University of Illinois Chicago17 papers (2013–2026)Bernie Devlin · University of Pittsburgh17 papers (2012–2025)Michael S. Breen · Beijing Obstetrics and Gynecology Hospital16 papers (2017–2022)Kathryn Roeder · University of Illinois Chicago15 papers (2012–2025)Behrang Mahjani · Norwegian Institute of Public Health15 papers (2017–2025)Hala Harony‐Nicolas · Allen Institute for Brain Science15 papers (2013–2021)Christina M. Hultman · Vanderbilt University Medical Center14 papers (2014–2022)Elodie Drapeau · Icahn School of Medicine at Mount Sinai13 papers (2013–2021)Tess Levy · Mount Sinai Hospital13 papers (2021–2025)Jessica Zweifach · Icahn School of Medicine at Mount Sinai13 papers (2013–2026)Latha Soorya · Rush University Medical Center12 papers (2012–2025)Patrick R. Hof · Allen Institute for Brain Science12 papers (2012–2021)Elizabeth Berry‐Kravis · Rush University Medical Center12 papers (2018–2025)Magdalena Janecka · New York University12 papers (2018–2025)