Area of research
Cardiology and Cardiovascular Medicine · Surgery
Research interest
Research interests include Tissue Engineering and Regenerative Medicine, Cardiac electrophysiology and arrhythmias, Cardiomyopathy and Myosin Studies, and Electrospun Nanofibers in Biomedical Applications.
Hypercontractility and Oxidative Stress Drive Creatine Kinase Dysfunction in Hypertrophic Cardiomyopathy
Metabolic Communication by SGLT2 Inhibition
The DZHK research platform: maximisation of scientific value by enabling access to health data and biological samples collected in cardiovascular clinical studies
PPARdelta activation induces metabolic and contractile maturation of human pluripotent stem cell-derived cardiomyocytes
Animal models and animal-free innovations for cardiovascular research: current status and routes to be explored. Consensus document of the ESC Working Group on Myocardial Function and the ESC Working Group on Cellular Biology of the Heart
Utrecht University Repository (Utrecht University) 2022cited by 66position: middle
Impairment of the ER/mitochondria compartment in human cardiomyocytes with PLN p.Arg14del mutation
In vivo grafting of large engineered heart tissue patches for cardiac repair
Targeted therapies in genetic dilated and hypertrophic cardiomyopathies: from molecular mechanisms to therapeutic targets. A position paper from the Heart Failure Association (HFA) and the Working Group on Myocardial Function of the European Society of Cardiology (ESC)
FYCO1 Regulates Cardiomyocyte Autophagy and Prevents Heart Failure Due to Pressure Overload In Vivo
Hypertrophic signaling compensates for contractile and metabolic consequences of DNA methyltransferase 3A loss in human cardiomyocytes
Generation of bi-allelic MYBPC3 truncating mutant and isogenic control from an iPSC line of a patient with hypertrophic cardiomyopathy
PPARdelta signaling activation improves metabolic and contractile maturation of human pluripotent stem cell-derived cardiomyocytes
Metabolic Maturation Media Improve Physiological Function of Human iPSC-Derived Cardiomyocytes
SARS-CoV-2 infects and induces cytotoxic effects in human cardiomyocytes
Towards standardization of echocardiography for the evaluation of left ventricular function in adult rodents: a position paper of the ESC Working Group on Myocardial Function
Common Mechanistic Pathways in Cancer and Heart Failure. A Scientific Roadmap on Behalf of the Translational Research Committee of the Heart Failure Association (HFA) of the European Society of Cardiology (ESC)
Targeting muscle-enriched long non-coding RNA <i>H19</i> reverses pathological cardiac hypertrophy
Aging-regulated anti-apoptotic long non-coding RNA Sarrah augments recovery from acute myocardial infarction
‘Corrigendum to “Ataxin-10 is part of a cachexokine cocktail triggering cardiac metabolic dysfunction in cancer cachexia” [Molecular Metabolism 5 (2) (2015) 67–78]’
ESC Working Group on Cellular Biology of the Heart: position paper for Cardiovascular Research: tissue engineering strategies combined with cell therapies for cardiac repair in ischaemic heart disease and heart failure
Long Noncoding RNA-Enriched Vesicles Secreted by Hypoxic Cardiomyocytes Drive Cardiac Fibrosis
Chronic intermittent tachypacing by an optogenetic approach induces arrhythmia vulnerability in human engineered heart tissue
Three-Dimensional Human iPSC-Derived Artificial Skeletal Muscles Model Muscular Dystrophies and Enable Multilineage Tissue Engineering
Treatments targeting inotropy
Pharmacological inhibition of DNA methylation attenuates pressure overload-induced cardiac hypertrophy in rats
Satellite cells delivered in their niche efficiently generate functional myotubes in three-dimensional cell culture
Cardiomyocyte Regeneration: A Consensus Statement.
Position Paper of the European Society of Cardiology Working Group Cellular Biology of the Heart: cell-based therapies for myocardial repair and regeneration in ischemic heart disease and heart failure
<i>S</i> ‐glutathiolation impairs phosphoregulation and function of cardiac myosin‐binding protein C in human heart failure
Development of Long Noncoding RNA-Based Strategies to Modulate Tissue Vascularization