Area of research
Cancer Research · Molecular Biology
Research interest
Research focused on microRNA and Heart failure, with related work in Microvesicles, Senescence, Gene silencing. Notable publications include 'Cardiac fibroblast–derived microRNA passenger strand-enriched exosomes mediate cardiomyocyte hypertrophy', 'The miRNA-212/132 family regulates both cardiac hypertrophy and cardiomyocyte autophagy', and 'Preclinical development of a miR-132 inhibitor for heart failure treatment'.
Structure-Based Design of PROTACS for the Degradation of Soluble Epoxide Hydrolase
Inhibition of miR-21: cardioprotective effects in human failing myocardium <i>ex vivo</i>
SGLT2 inhibitors attenuate endothelial to mesenchymal transition and cardiac fibroblast activation
Single-nucleus RNA sequencing identifies cell-type–specific effects of sodium-glucose co-transporter 2 inhibitors in human myocardial slices
Circulating microRNAs predispose to takotsubo syndrome following high-dose adrenaline exposure
Alternative strategies in cardiac preclinical research and new clinical trial formats
Preclinical development of a miR-132 inhibitor for heart failure treatment
Natural Compound Library Screening Identifies New Molecules for the Treatment of Cardiac Fibrosis and Diastolic Dysfunction
Inflammatory Drivers of Cardiovascular Disease: Molecular Characterization of Senescent Coronary Vascular Smooth Muscle Cells
Senescence-induced inflammation: an important player and key therapeutic target in atherosclerosis
Attenuated palmitoylation of serotonin receptor 5-HT1A affects receptor function and contributes to depression-like behaviors
Hypoxia-Induced MicroRNA-212/132 Alter Blood-Brain Barrier Integrity Through Inhibition of Tight Junction-Associated Proteins in Human and Mouse Brain Microvascular Endothelial Cells
Long Noncoding RNA-Enriched Vesicles Secreted by Hypoxic Cardiomyocytes Drive Cardiac Fibrosis
Serum circular RNAs act as blood-based biomarkers for hypertrophic obstructive cardiomyopathy
Non‐coding RNAs: key players in cardiac disease
Circulating non-coding RNAs in biomarker-guided cardiovascular therapy: a novel tool for personalized medicine?
Non-coding RNAs in vascular disease – from basic science to clinical applications: scientific update from the Working Group of Myocardial Function of the European Society of Cardiology
Podocytes regulate the glomerular basement membrane protein nephronectin by means of miR-378a-3p in glomerular diseases
MicroRNAs regulating superoxide dismutase 2 are new circulating biomarkers of heart failure
miR-21 promotes fibrosis in an acute cardiac allograft transplantation model
Stiff matrix induces switch to pure β-cardiac myosin heavy chain expression in human ESC-derived cardiomyocytes
MicroRNA-Based Therapy of GATA2-Deficient Vascular Disease
New Insights Into miR-17–92 Cluster Regulation and Angiogenesis
Osteopontin is indispensible for AP1-mediated angiotensin II-related miR-21 transcription during cardiac fibrosis
Development of Long Noncoding RNA-Based Strategies to Modulate Tissue Vascularization
Deciphering the microRNA signature of pathological cardiac hypertrophy by engineered heart tissue- and sequencing-technology
Cardiac fibroblast–derived microRNA passenger strand-enriched exosomes mediate cardiomyocyte hypertrophy
MicroRNA-24 Antagonism Prevents Renal Ischemia Reperfusion Injury
Circulating Long Noncoding RNA TapSAKI Is a Predictor of Mortality in Critically Ill Patients with Acute Kidney Injury
MicroRNAs in Myocardial Infarction