Area of research
Molecular Biology · Hematology
Research interest
Research interests include Ubiquitin and proteasome pathways, Cell death mechanisms and regulation, Protein Degradation and Inhibitors, and Multiple Myeloma Research and Treatments.
Development of an Imidazopyridazine-Based MNK1/2 Inhibitor for the Treatment of Lymphoma
Discovery of ARD-1676 as a Highly Potent and Orally Efficacious AR PROTAC Degrader with a Broad Activity against AR Mutants for the Treatment of AR + Human Prostate Cancer
Lisaftoclax (APG-2575) Is a Novel BCL-2 Inhibitor with Robust Antitumor Activity in Preclinical Models of Hematologic Malignancy
Targeted Degradation of BET Proteins in Triple-Negative Breast Cancer
Design of High-Affinity Stapled Peptides To Target the Repressor Activator Protein 1 (RAP1)/Telomeric Repeat-Binding Factor 2 (TRF2) Protein–Protein Interaction in the Shelterin Complex