Area of research
Molecular Biology · Genetics
Research interest
Research interests include CRISPR and Genetic Engineering, Advanced biosensing and bioanalysis techniques, RNA and protein synthesis mechanisms, and Virus-based gene therapy research.
Systematic optimization of prime editing for the efficient functional correction of CFTR F508del in human airway epithelial cells
Author Correction: Adenine transversion editors enable precise, efficient A•T-to-C•G base editing in mammalian cells and embryos
Ex vivo prime editing of patient haematopoietic stem cells rescues sickle-cell disease phenotypes after engraftment in mice
Adenine transversion editors enable precise, efficient A•T-to-C•G base editing in mammalian cells and embryos
Designing and executing prime editing experiments in mammalian cells
Search-and-replace genome editing without double-strand breaks or donor DNA
Engineered CRISPR–Cas12a variants with increased activities and improved targeting ranges for gene, epigenetic and base editing
High levels of AAV vector integration into CRISPR-induced DNA breaks
Prediction of off-target activities for the end-to-end design of CRISPR guide RNAs
Discovery of widespread type I and type V CRISPR-Cas inhibitors
Enhanced proofreading governs CRISPR–Cas9 targeting accuracy