Area of research
Genetics · Epidemiology
Research interest
Research interests include Inflammatory Bowel Disease, Genetic Associations and Epidemiology, Microscopic Colitis, and Immunodeficiency and Autoimmune Disorders.
Comprehensive Association Analyses of Extraintestinal Manifestations in Inflammatory Bowel Disease
Eleven Grand Challenges for Inflammatory Bowel Disease Genetics and Genomics
Ancestral Diversity in Pharmacogenomics Affects Treatment for Hispanic/Latine Populations With Inflammatory Bowel Disease
Genetic coding variant in complement factor B (CFB) is associated with increased risk for perianal Crohn’s disease and leads to impaired CFB cleavage and phagocytosis
Identifying high-impact variants and genes in exomes of Ashkenazi Jewish inflammatory bowel disease patients
Large-scale sequencing identifies multiple genes and rare variants associated with Crohn’s disease susceptibility
Inflamed Ulcerative Colitis Regions Associated With MRGPRX2-Mediated Mast Cell Degranulation and Cell Activation Modules, Defining a New Therapeutic Target
Whole-genome sequencing of African Americans implicates differential genetic architecture in inflammatory bowel disease
Transethnic analysis of the human leukocyte antigen region for ulcerative colitis reveals not only shared but also ethnicity-specific disease associations
Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry
Serum Analyte Profiles Associated With Crohn’s Disease and Disease Location
Altered Intestinal ACE2 Levels Are Associated With Inflammation, Severe Disease, and Response to Anti-Cytokine Therapy in Inflammatory Bowel Disease
Comparative performances of machine learning methods for classifying Crohn Disease patients using genome-wide genotyping data
Functional variants in the <i>LRRK2</i> gene confer shared effects on risk for Crohn’s disease and Parkinson’s disease
IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes
Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population
Fine-mapping inflammatory bowel disease loci to single-variant resolution
Genome-Wide Association Study Identifies African-Specific Susceptibility Loci in African Americans With Inflammatory Bowel Disease
A Pleiotropic Missense Variant in SLC39A8 Is Associated With Crohn’s Disease and Human Gut Microbiome Composition
A Frameshift in CSF2RB Predominant Among Ashkenazi Jews Increases Risk for Crohn's Disease and Reduces Monocyte Signaling via GM-CSF
A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis
Increased Prevalence of Inflammatory Bowel Disease in Patients with Mutations in Genes Encoding the Receptor Subunits for TGFβ
A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration
Characterization of Genetic Loci That Affect Susceptibility to Inflammatory Bowel Diseases in African Americans
Ocular Manifestations in Inflammatory Bowel Disease Are Associated with Other Extra-intestinal Manifestations, Gender, and Genes Implicated in Other Immune-related Traits
Reprograming of gut microbiome energy metabolism by the <i>FUT2</i> Crohn’s disease risk polymorphism
Genetic Variants Associated With Quantitative Glucose Homeostasis Traits Translate to Type 2 Diabetes in Mexican Americans: The GUARDIAN (Genetics Underlying Diabetes in Hispanics) Consortium
Immunochip Analysis Identification of 6 Additional Susceptibility Loci for Crohnʼs Disease in Koreans
A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry
Best Practices and Joint Calling of the HumanExome BeadChip: The CHARGE Consortium