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John Varga

Northwestern University · US
Area of research
Pathology and Forensic Medicine · Pulmonary and Respiratory Medicine
Research interest
Research interests include Systemic Sclerosis and Related Diseases, Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis, Connective Tissue Growth Factor Research, and Inflammatory Myopathies and Dermatomyositis.
h-index
94
citations
33,092
works
454
NIH funding
primary concept
email

Recent publications

2023 American College of Rheumatology (ACR)/American College of Chest Physicians (CHEST) Guideline for the Treatment of Interstitial Lung Disease in People with Systemic Autoimmune Rheumatic Diseases
Arthritis & Rheumatology 2024cited by 156position: middledoi
2023 American College of Rheumatology (<scp>ACR</scp>)/American College of Chest Physicians (<scp>CHEST</scp>) Guideline for the Screening and Monitoring of Interstitial Lung Disease in People with Systemic Autoimmune Rheumatic Diseases
Arthritis & Rheumatology 2024cited by 116position: middledoi
Systems-based identification of the Hippo pathway for promoting fibrotic mesenchymal differentiation in systemic sclerosis
Nature Communications 2024cited by 73position: middledoi
2023 American College of Rheumatology (ACR)/American College of Chest Physicians (CHEST) Guideline for the Screening and Monitoring of Interstitial Lung Disease in People with Systemic Autoimmune Rheumatic Diseases
Arthritis Care & Research 2024cited by 66position: middledoi
749 The metaorganismal TMAO pathway links fibrosis and the gut in systemic sclerosis
Journal of Investigative Dermatology 2024cited by 0position: lastdoi
Biological and clinical insights from a randomized phase 2 study of an anti-oncostatin M monoclonal antibody in systemic sclerosis
Lara D. Veeken 2022cited by 33position: middledoi
<scp>Adipose‐Derived</scp> Regenerative Cell Transplantation for the Treatment of Hand Dysfunction in Systemic Sclerosis: A Randomized Clinical Trial
Arthritis & Rheumatology 2022cited by 25position: middledoi
Fibroblast A20 governs fibrosis susceptibility and its repression by DREAM promotes fibrosis in multiple organs
Nature Communications 2022cited by 20position: lastdoi
Reduced SPAG17 Expression in Systemic Sclerosis Triggers Myofibroblast Transition and Drives Fibrosis
Journal of Investigative Dermatology 2022cited by 13position: lastdoi
Clinical characteristics, visceral involvement, and mortality in at-risk or early diffuse systemic sclerosis: a longitudinal analysis of an observational prospective multicenter US cohort
Arthritis Research & Therapy 2021cited by 67position: middledoi
Effects of a multi-faceted education and support programme on anxiety symptoms among people with systemic sclerosis and anxiety during COVID-19 (SPIN-CHAT): a two-arm parallel, partially nested, randomised, controlled trial
The Lancet Rheumatology 2021cited by 38position: middledoi
Changes in mental health symptoms from pre-COVID-19 to COVID-19 among participants with systemic sclerosis from four countries: A Scleroderma Patient-centered Intervention Network (SPIN) Cohort study
Journal of Psychosomatic Research 2020cited by 44position: middledoi
Etiology, Risk Factors, and Biomarkers in Systemic Sclerosis with Interstitial Lung Disease
American Journal of Respiratory and Critical Care Medicine 2019cited by 191position: lastdoi
Emerging targets of disease-modifying therapy for systemic sclerosis
Nature Reviews Rheumatology 2019cited by 129position: lastdoi
Generation of a Core Set of Items to Develop Classification Criteria for Scleroderma Renal Crisis Using Consensus Methodology
Arthritis & Rheumatology 2019cited by 81position: middledoi
Myeloablation followed by autologous stem cell transplantation normalises systemic sclerosis molecular signatures
Annals of the Rheumatic Diseases 2019cited by 68position: middledoi
TLR4-dependent fibroblast activation drives persistent organ fibrosis in skin and lung
JCI Insight 2018cited by 134position: lastdoi
Pathogenesis of systemic sclerosis: recent insights of molecular and cellular mechanisms and therapeutic opportunities
Journal of Scleroderma and Related Disorders 2017cited by 322position: firstdoi
Clinical and serological features of systemic sclerosis in a multicenter African American cohort
Medicine 2017cited by 113position: middledoi
Novel lung imaging biomarkers and skin gene expression subsetting in dasatinib treatment of systemic sclerosis-associated interstitial lung disease
PLoS ONE 2017cited by 71position: lastdoi
Design of a randomised, placebo-controlled clinical trial of nintedanib in patients with systemic sclerosis-associated interstitial lung disease (SENSCIS™).
PubMed 2017cited by 70position: middle
Inhibition of β-Catenin Signaling in the Skin Rescues Cutaneous Adipogenesis in Systemic Sclerosis: A Randomized, Double-Blind, Placebo-Controlled Trial of C-82
Journal of Investigative Dermatology 2017cited by 51position: lastdoi
Digital Ulcers in Ssc Treated with Oral Treprostinil: A Randomized, Double-Blind, Placebo-Controlled Study with Open-Label Follow-up
Journal of Scleroderma and Related Disorders 2017cited by 36position: middledoi
Mycophenolate mofetil versus oral cyclophosphamide in scleroderma-related interstitial lung disease (SLS II): a randomised controlled, double-blind, parallel group trial
The Lancet Respiratory Medicine 2016cited by 1,051position: middledoi
Tenascin-C drives persistence of organ fibrosis
Nature Communications 2016cited by 288position: lastdoi
SIRT3 is attenuated in systemic sclerosis skin and lungs, and its pharmacologic activation mitigates organ fibrosis
Oncotarget 2016cited by 108position: lastdoi
Toll‐like Receptor 9 Signaling Is Augmented in Systemic Sclerosis and Elicits Transforming Growth Factor β–Dependent Fibroblast Activation
Arthritis & Rheumatology 2016cited by 66position: lastdoi
Identification of Optimal Mouse Models of Systemic Sclerosis by Interspecies Comparative Genomics
Arthritis & Rheumatology 2016cited by 42position: middledoi
Genetic susceptibility loci of idiopathic interstitial pneumonia do not represent risk for systemic sclerosis: a case control study in Caucasian patients
Arthritis Research & Therapy 2016cited by 22position: middledoi
Systemic sclerosis
Nature Reviews Disease Primers 2015cited by 851position: lastdoi

Grants

No grants ingested yet.

Frequent collaborators

Swati Bhattacharyya · University of Michigan–Ann Arbor10 papers (2012–2024)Monique Hinchcliff · Yale University8 papers (2013–2021)Dinesh Khanna · University of Michigan8 papers (2013–2024)Robert Lafyatis · La Roche College7 papers (2012–2024)Jun Wei · Nanjing University of Chinese Medicine7 papers (2012–2022)Virginia Steen · Georgetown University5 papers (2013–2022) · 5 papers (2012–2018)Robert W. Simms · Boston University5 papers (2013–2022)Roberta Gonçalves Marangoni · University of Rochester Medical Center5 papers (2012–2022)Shervin Assassi · University of Houston4 papers (2017–2022)Robyn T. Domsic · University of Pittsburgh4 papers (2013–2022)Michael L. Whitfield · Dartmouth College4 papers (2013–2017)Wenxia Wang · Northwestern University4 papers (2016–2022) · 4 papers (2012–2016)Christopher P. Denton · University of Leeds4 papers (2015–2022)Mary Carns · Henry Ford Health System3 papers (2013–2022)Maureen D. Mayes · The University of Texas Health Science Center3 papers (2014–2022)Chris T. Derk · Georgetown University3 papers (2013–2022)Vivien Hsu · Rutgers, The State University of New Jersey3 papers (2013–2022)Tracy Frech · Vanderbilt University3 papers (2013–2021)