Area of research
Molecular Biology · Computational Theory and Mathematics
Research interest
Research interests include DNA Repair Mechanisms, Computational Drug Discovery Methods, Click Chemistry and Applications, and Metabolomics and Mass Spectrometry Studies.
Small-molecule activation of OGG1 increases oxidative DNA damage repair by gaining a new function
Targeting OGG1 arrests cancer cell proliferation by inducing replication stress
Novel Broad-Spectrum Antiviral Inhibitors Targeting Host Factors Essential for Replication of Pathogenic RNA Viruses
Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation
Targeting BER enzymes in cancer therapy
Validation and development of MTH1 inhibitors for treatment of cancer
The PARP inhibitor Olaparib disrupts base excision repair of 5-aza-2′-deoxycytidine lesions