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Utpal B. Pajvani

Columbia University Irving Medical Center · US
Area of research
Epidemiology · Surgery
Research interest
Research interests include Liver Disease Diagnosis and Treatment, Pancreatic function and diabetes, Adipose Tissue and Metabolism, and Adipokines, Inflammation, and Metabolic Diseases.
h-index
42
citations
13,259
works
98
NIH funding
primary concept
Medicine
email

Recent publications

Unraveling A-β+ ketosis-prone diabetes: An evolving diagnosis with an elusive pathogenesis.
2026cited by 0position: contributordoi
Hepatic stellate cells control liver zonation, size and functions via R-spondin 3
Nature 2025cited by 73position: middledoi
Integrative Genomic and Transcriptomic Analysis Reveals Targetable Vulnerabilities in Angioimmunoblastic T‐Cell Lymphoma
American Journal of Hematology 2025cited by 6position: middledoi
Diabetes mellitus—Progress and opportunities in the evolving epidemic
Cell 2024cited by 222position: middledoi
The first MASH drug therapy on the horizon: Current perspectives of resmetirom.
2024cited by 117position: contributordoi
β-cell Jagged1 is sufficient but not necessary for islet Notch activity and insulin secretory defects in obese mice.
2024cited by 4position: contributordoi
Kisspeptin Alleviates Human Hepatic Fibrogenesis by Inhibiting TGFβ Signaling in Hepatic Stellate Cells.
2024cited by 3position: contributordoi
Kisspeptin Alleviates Human Hepatic Fibrogenesis by Inhibiting TGFb Signaling in Hepatic Stellate Cells
2024cited by 0position: contributordoi
Calorie restriction activates a gastric Notch-FOXO1 pathway to expand ghrelin cells.
2024cited by 0position: contributordoi
Notch-mediated hepatocyte MCP-1 secretion causes liver fibrosis.
2023cited by 58position: contributordoi
Opposing roles of hepatic stellate cell subpopulations in hepatocarcinogenesis
Nature 2022cited by 322position: middledoi
TAZ-induced Cybb contributes to liver tumor formation in non-alcoholic steatohepatitis.
2022cited by 34position: contributordoi
Notch-mediated Ephrin signaling disrupts islet architecture and β cell function.
2022cited by 12position: contributordoi
Hepatocyte TLR4 triggers inter-hepatocyte Jagged1/Notch signaling to determine NASH-induced fibrosis
Science Translational Medicine 2021cited by 120position: lastdoi
Hepatocyte TLR4 triggers inter-hepatocyte Jagged1/Notch signaling to determine NASH-induced fibrosis.
2021cited by 105position: contributordoi
Maladaptive regeneration - the reawakening of developmental pathways in NASH and fibrosis.
2021cited by 92position: contributordoi
Notch activity characterizes a common hepatocellular carcinoma subtype with unique molecular and clinicopathologic features.
2021cited by 52position: contributordoi
Metformin Is Associated With a Lower Risk of Atrial Fibrillation and Ventricular Arrhythmias Compared With Sulfonylureas: An Observational Study.
2021cited by 41position: contributordoi
Adipocyte PHLPP2 inhibition prevents obesity-induced fatty liver.
2021cited by 28position: contributordoi
Diabetic ketoacidosis and mortality in COVID-19 infection.
2021cited by 27position: contributordoi
A genetic hypothesis for burnt-out steatohepatitis.
2021cited by 12position: contributordoi
MTOR and Beta Cell Adaptation in T2D.
2021cited by 2position: contributordoi
Cholesterol Stabilizes TAZ in Hepatocytes to Promote Experimental Non-alcoholic Steatohepatitis
Cell Metabolism 2020cited by 198position: middledoi
Notch activity characterizes a common hepatocellular carcinoma subtype with unique molecular and clinicopathologic features
Journal of Hepatology 2020cited by 64position: lastdoi
Targeted Delivery of Notch Inhibitor Attenuates Obesity-Induced Glucose Intolerance and Liver Fibrosis
ACS Nano 2020cited by 57position: lastdoi
Targeted Delivery of Notch Inhibitor Attenuates Obesity-Induced Glucose Intolerance and Liver Fibrosis.
2020cited by 47position: contributordoi
Inhibition of γ-secretase in adipocytes leads to altered IL-6 secretion and adipose inflammation.
2020cited by 2position: contributordoi
Angiotensin converting enzyme 2 is a novel target of the γ-secretase complex
2020cited by 2position: contributordoi
Hepatocyte Notch activation induces liver fibrosis in nonalcoholic steatohepatitis
Science Translational Medicine 2018cited by 242position: lastdoi
Degradation of PHLPP2 by KCTD17, via a Glucagon-Dependent Pathway, Promotes Hepatic Steatosis
Gastroenterology 2017cited by 44position: lastdoi

Grants

No grants ingested yet.

Frequent collaborators

· 20 papers (2020–2026)Xiaobo Wang · Dali University5 papers (2018–2022)Luca V. C. Valenti · Memorial Hospital5 papers (2021–2024)Changyu Zhu · Inner Mongolia Electric Power (China)5 papers (2021–2023)KyeongJin Kim · Columbia University4 papers (2016–2021)Luca Valenti · Memorial Hospital4 papers (2017–2021)Changyu Zhu · University of Electronic Science and Technology of China4 papers (2018–2021)Junjie Yu · Qinghai University4 papers (2021–2024)Alberto Bartolomé · Columbia University4 papers (2020–2023)Li Qiang · Peking University3 papers (2016–2021) · 3 papers (2017–2021)Robert F. Schwabe · Columbia University Irving Medical Center3 papers (2018–2020)Ira Tabas · Columbia University Irving Medical Center3 papers (2018–2021)Alberto Bartolomé · Columbia University3 papers (2018–2021)Ira A Tabas · Institute of Molecular Medicine3 papers (2021–2022)Joel E. Lavine · Ithaca College2 papers (2018–2021)Scott W. Lowe · Memorial Sloan Kettering Cancer Center2 papers (2020–2021)Marcela Salomao · Columbia University2 papers (2018–2020)Scott L. Friedman · Mount Sinai Health System2 papers (2024–2024)Katherine P. Yates · Indiana University2 papers (2018–2021)