Area of research
Hepatology · Epidemiology
Research interest
Research interests include Liver Disease Diagnosis and Treatment, Liver physiology and pathology, Organ Transplantation Techniques and Outcomes, and Liver Diseases and Immunity.
Hepatic stellate cells control liver zonation, size and functions via R-spondin 3
Hepatic stellate cells: balancing homeostasis, hepatoprotection and fibrogenesis in health and disease
Immunology and immunotherapy of cholangiocarcinoma
Immune mechanisms linking metabolic injury to inflammation and fibrosis in fatty liver disease – novel insights into cellular communication circuits
Opposing roles of hepatic stellate cell subpopulations in hepatocarcinogenesis
Collagenolysis-dependent DDR1 signalling dictates pancreatic cancer outcome
The purinergic P2Y14 receptor links hepatocyte death to hepatic stellate cell activation and fibrogenesis in the liver
β-Catenin Sustains and Is Required for YES-associated Protein Oncogenic Activity in Cholangiocarcinoma
Effect of rifaximin on infections, acute‐on‐chronic liver failure and mortality in alcoholic hepatitis: A pilot study (RIFA‐AH)
Enterohepatic Shunt-Driven Cholemia Predisposes to Liver Cancer
Mouse model of NASH that replicates key features of the human disease and progresses to fibrosis stage 3
A molecular single-cell lung atlas of lethal COVID-19
Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations
Tumor restriction by type I collagen opposes tumor-promoting effects of cancer-associated fibroblasts
Focal adhesion kinase (FAK) promotes cholangiocarcinoma development and progression via YAP activation
Cholesterol Stabilizes TAZ in Hepatocytes to Promote Experimental Non-alcoholic Steatohepatitis
Notch activity characterizes a common hepatocellular carcinoma subtype with unique molecular and clinicopathologic features
c-Rel orchestrates energy-dependent epithelial and macrophage reprogramming in fibrosis
Macrophage MerTK Promotes Liver Fibrosis in Nonalcoholic Steatohepatitis
Hepatocyte Notch activation induces liver fibrosis in nonalcoholic steatohepatitis
NLR Family Pyrin Domain‐Containing 3 Inflammasome Activation in Hepatic Stellate Cells Induces Liver Fibrosis in Mice
The nucleoprotein High-mobility group box 1 critically regulates the immune response to bacterial infection
MicroRNA‐21 and Dicer are dispensable for hepatic stellate cell activation and the development of liver fibrosis
Hepatocyte TAZ/WWTR1 Promotes Inflammation and Fibrosis in Nonalcoholic Steatohepatitis
Direct Reprogramming of Hepatic Myofibroblasts into Hepatocytes In Vivo Attenuates Liver Fibrosis
In Vivo Hepatic Reprogramming of Myofibroblasts with AAV Vectors as a Therapeutic Strategy for Liver Fibrosis
Opposite roles of cannabinoid receptors 1 and 2 in hepatocarcinogenesis
Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance
Gremlin 1 Identifies a Skeletal Stem Cell with Bone, Cartilage, and Reticular Stromal Potential
Hepatic inflammation and fibrosis: Functional links and key pathways