Jinyin Ge

Area of research

Spectroscopy · Materials Chemistry

Research interest

Research topics from publications: A Water‐Soluble AIEgen for Noninvasive Diagnosis of Kidney Fibrosis via SWIR Fluorescence and Photoacoustic Imaging; Viscosity-responsive NIR-II fluorescent probe with aggregation-induced emission features for early diagnosis of liver injury; A benzimidazole-based ratiometric fluorescent probe for the accurate and rapid monitoring of lysosomal pH in cell autophagy and anticounterfeiting; A viscosity-activable nano-micelle with aggregation-induced emission for boosting NIR-II fluorescence imaging-guided synergetic photodynamic/photothermal therapy of breast cancer. Representative work: Early diagnosis of renal fibrosis is crucially significant on account of its worldwide prevalent tendency. Optical imaging in the near-infrared window has been recognized as an appealing technique for the timely detection of renal dysfunction. However, formulating a contrast agent that allows early monitoring of renal fibrosis and concurrently renally clearable in a normal group is still challenging. Herein, a nanosized fluorophore with aggregation-induced emission (AIE) features, namely AIE-4PEG550 NPs, is well-tailored and amenable to longitudinal visualization of the fibrosis progression specifically in the early-stage via short-wave infrared (SWIR, 900-1700 nm) fluorescence and photoacou The lysosomal targeted ratiometric fluorescent BD probe reveals excellent application performance in the fields of selective monitoring of the lysosome pH of living cells, real-time dynamic monitoring of autophagy, and document anti-counterfeiting