Area of research
Psychiatry and Mental health · Physiology
Research interest
Research interests include Biology, Neuroscience, Disease, Alzheimer's disease, Transcriptome, and Neurodegeneration.
Cell subtype-specific effects of genetic variation in the Alzheimer’s disease brain
Cellular communities reveal trajectories of brain ageing and Alzheimer’s disease
Human microglial state dynamics in Alzheimer’s disease progression
Epigenomic dissection of Alzheimer’s disease pinpoints causal variants and reveals epigenome erosion
Single-nucleus multiregion transcriptomic analysis of brain vasculature in Alzheimer’s disease
Neuronal DNA double-strand breaks lead to genome structural variations and 3D genome disruption in neurodegeneration
Multicellular communities are perturbed in the aging human brain and Alzheimer’s disease
Genome-wide structural variant analysis identifies risk loci for non-Alzheimer’s dementias
Lateral mammillary body neurons in mouse brain are disproportionately vulnerable in Alzheimer’s disease
APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes
Single-cell dissection of the human brain vasculature
Risk Models Based on Non-Cognitive Measures May Identify Presymptomatic Alzheimer’s Disease
Risk models based on non-cognitive measures may identify presymptomatic Alzheimer’s disease
MEF2 is a key regulator of cognitive potential and confers resilience to neurodegeneration
Large eQTL meta-analysis reveals differing patterns between cerebral cortical and cerebellar brain regions
Meta-Analysis of the Alzheimer’s Disease Human Brain Transcriptome and Functional Dissection in Mouse Models
Single-cell transcriptomic analysis of Alzheimer’s disease
3D mapping reveals network-specific amyloid progression and subcortical susceptibility in mice
Author Correction: Single-cell transcriptomic analysis of Alzheimer’s disease
Epigenome-wide study uncovers large-scale changes in histone acetylation driven by tau pathology in aging and Alzheimer’s human brains
Cell-type Dependent Alzheimer's Disease Phenotypes: Probing the Biology of Selective Neuronal Vulnerability
Crowdsourced estimation of cognitive decline and resilience in Alzheimer's disease
Global and local ancestry in African‐Americans: Implications for Alzheimer's disease risk
Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci