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Deepu Madduri

Johnson & Johnson (United States) · US
Area of research
Hematology · Oncology
Research interest
Research interests include Multiple Myeloma Research and Treatments, CAR-T cell therapy research, Protein Degradation and Inhibitors, and Biosimilars and Bioanalytical Methods.
h-index
35
citations
12,648
works
166
NIH funding
primary concept
Medicine
email

Recent publications

Long-Term (≥5-Year) Remission and Survival After Treatment With Ciltacabtagene Autoleucel in CARTITUDE-1 Patients With Relapsed/Refractory Multiple Myeloma
Journal of Clinical Oncology 2025cited by 66position: middledoi
Long-term (≥5 year) remission and survival after treatment with ciltacabtagene autoleucel (cilta-cel) in CARTITUDE-1 patients (pts) with relapsed/refractory multiple myeloma (RRMM).
Journal of Clinical Oncology 2025cited by 9position: middledoi
Clinical Experience with Cranial Nerve Impairment in the Cartitude-1, Cartitude-2 Cohorts a, B and C, and Cartitude-4 Studies of Ciltacabtagene Autoleucel (Cilta-cel)
Transplantation and Cellular Therapy 2024cited by 10position: middledoi
The Phase 2 Cartitude-2 Trial: Updated Efficacy and Safety of Ciltacabtagene Autoleucel in Patients with Multiple Myeloma and 1–3 Prior Lines of Therapy (Cohort A) and with Early Relapse after First Line Treatment (Cohort B)
Transplantation and Cellular Therapy 2024cited by 5position: middledoi
CARTITUDE-1 final results: Phase 1b/2 study of ciltacabtagene autoleucel in heavily pretreated patients with relapsed/refractory multiple myeloma.
Journal of Clinical Oncology 2023cited by 111position: middledoi
Idecabtagene vicleucel for relapsed and refractory multiple myeloma: post hoc 18-month follow-up of a phase 1 trial.
2023cited by 94position: contributordoi
The Phase 2 CARTITUDE-2 Trial: Updated Efficacy and Safety of Ciltacabtagene Autoleucel in Patients with Multiple Myeloma and 1-3 Prior Lines of Therapy (Cohort A) and with Early Relapse after First Line Treatment (Cohort B)
Blood 2023cited by 29position: middledoi
S202: CARTITUDE-1 FINAL RESULTS: PHASE 1B/2 STUDY OF CILTACABTAGENE AUTOLEUCEL IN HEAVILY PRETREATED PATIENTS WITH RELAPSED/REFRACTORY MULTIPLE MYELOMA
HemaSphere 2023cited by 15position: middledoi
P23 EMAGINE/CARTITUDE-6: A RANDOMIZED PHASE 3 STUDY OF DVRD FOLLOWED BY CILTACABTAGENE AUTOLEUCEL VERSUS DVRD FOLLOWED BY AUTOLOGOUS STEM CELL TRANSPLANT IN TRANSPLANT-ELIGIBLE PATIENTS WITH NEWLY DIAGNOSED MULTIPLE MYELOMA
HemaSphere 2023cited by 14position: middledoi
Ciltacabtagene Autoleucel, an Anti–B-cell Maturation Antigen Chimeric Antigen Receptor T-Cell Therapy, for Relapsed/Refractory Multiple Myeloma: CARTITUDE-1 2-Year Follow-Up
Journal of Clinical Oncology 2022cited by 618position: middledoi
Incidence and management of CAR-T neurotoxicity in patients with multiple myeloma treated with ciltacabtagene autoleucel in CARTITUDE studies
Blood Cancer Journal 2022cited by 263position: middledoi
Health-related quality of life in patients given ciltacabtagene autoleucel for relapsed or refractory multiple myeloma (CARTITUDE-1): a phase 1b–2, open-label study
The Lancet Haematology 2022cited by 44position: middledoi
Anti-Granulocyte–Macrophage Colony–Stimulating Factor Monoclonal Antibody Gimsilumab for COVID-19 Pneumonia: A Randomized, Double-Blind, Placebo-controlled Trial
2022cited by 29position: middle
DVRd Followed By Ciltacabtagene Autoleucel Versus DVRd Followed By ASCT in Patients with Newly Diagnosed Multiple Myeloma Who Are Transplant Eligible: A Randomized Phase 3 Study (<i>EM</i>agine/CARTITUDE-6)
Blood 2022cited by 21position: middledoi
Patient Perceptions Regarding Ciltacabtagene Autoleucel Treatment: Qualitative Evidence From Interviews With Patients With Relapsed/Refractory Multiple Myeloma in the CARTITUDE-1 Study
Clinical Lymphoma Myeloma & Leukemia 2022cited by 17position: middledoi
A three gene signature predicts response to selinexor in multiple myeloma
2022cited by 0position: contributordoi
Idecabtagene Vicleucel in Relapsed and Refractory Multiple Myeloma
New England Journal of Medicine 2021cited by 2,368position: middledoi
Ciltacabtagene autoleucel, a B-cell maturation antigen-directed chimeric antigen receptor T-cell therapy in patients with relapsed or refractory multiple myeloma (CARTITUDE-1): a phase 1b/2 open-label study
The Lancet 2021cited by 1,626position: middledoi
Ciltacabtagene autoleucel, a B-cell maturation antigen-directed chimeric antigen receptor T-cell therapy in patients with relapsed or refractory multiple myeloma (CARTITUDE-1): a phase 1b/2 open-label study.
2021cited by 1,284position: contributordoi
Neurocognitive and hypokinetic movement disorder with features of parkinsonism after BCMA-targeting CAR-T cell therapy
Nature Medicine 2021cited by 248position: middledoi
Updated Results from CARTITUDE-1: Phase 1b/2Study of Ciltacabtagene Autoleucel, a B-Cell Maturation Antigen-Directed Chimeric Antigen Receptor T Cell Therapy, in Patients With Relapsed/Refractory Multiple Myeloma
Blood 2021cited by 66position: middledoi
Ciltacabtagene autoleucel, a B-cell maturation antigen (BCMA)-directed chimeric antigen receptor T-cell (CAR-T) therapy, in relapsed/refractory multiple myeloma (R/R MM): Updated results from CARTITUDE-1.
Journal of Clinical Oncology 2021cited by 35position: middledoi
Real-world treatment patterns, healthcare use and costs in triple-class exposed relapsed and refractory multiple myeloma patients in the USA.
2021cited by 27position: contributordoi
UPDATED RESULTS FROM THE CARTITUDE-1 STUDY OF CILTACABTAGENE AUTOLEUCEL, A B-CELL MATURATION ANTIGEN–DIRECTED CHIMERIC ANTIGEN RECEPTOR T CELL THERAPY, IN RELAPSED/REFRACTORY MULTIPLE MYELOMA
Hematology Transfusion and Cell Therapy 2021cited by 21position: middledoi
Subcutaneous daratumumab and hyaluronidase-fihj in newly diagnosed or relapsed/refractory multiple myeloma.
2021cited by 7position: contributordoi
OAB-023: Efficacy and safety of ciltacabtagene autoleucel, a BCMA-directed CAR-T cell therapy, in patients with progressive multiple myeloma after 1–3 prior lines of therapy: Initial results from CARTITUDE-2
Clinical Lymphoma Myeloma & Leukemia 2021cited by 0position: middledoi
A Phase 1 First in Human (FIH) Study of AMG 701, an Anti-B-Cell Maturation Antigen (BCMA) Half-Life Extended (HLE) BiTE® (bispecific T-cell engager) Molecule, in Relapsed/Refractory (RR) Multiple Myeloma (MM)
Blood 2020cited by 112position: middledoi
A tertiary center experience of multiple myeloma patients with COVID-19: lessons learned and the path forward.
2020cited by 106position: contributordoi
CARTITUDE-1: Phase 1b/2 Study of Ciltacabtagene Autoleucel, a B-Cell Maturation Antigen-Directed Chimeric Antigen Receptor T Cell Therapy, in Relapsed/Refractory Multiple Myeloma
Blood 2020cited by 93position: firstdoi
Updated Results from the Phase I CRB-402 Study of Anti-Bcma CAR-T Cell Therapy bb21217 in Patients with Relapsed and Refractory Multiple Myeloma: Correlation of Expansion and Duration of Response with T Cell Phenotypes
Blood 2020cited by 85position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Sundar Jagannath · All India Institute of Medical Sciences21 papers (2018–2025)Jesús G. Berdeja · The Centers16 papers (2018–2025)Andrzej Jakubowiak · Palmetto Hematology Oncology13 papers (2019–2025)Nikhil C. Munshi · Harvard University9 papers (2018–2023)Jordan M. Schecter · Johnson & Johnson (Israel)9 papers (2019–2023)Yi Lin · South China Agricultural University9 papers (2018–2023)Enrique Zudaire · Caribou Biosciences (United States)8 papers (2019–2023)Adam D. Cohen · Texas Children's Hospital8 papers (2021–2025)Noopur Raje · Harvard University8 papers (2018–2025)David S. Siegel · Universidade Federal de Santa Catarina7 papers (2018–2020)Kristen Hege · Independent Sector7 papers (2018–2020)Arnob Banerjee · Janssen (United States)7 papers (2019–2023)Fabio Petrocca · Bristol-Myers Squibb (Sweden)7 papers (2018–2020)Ashley Turka · Bluebird Bio (United States)7 papers (2018–2020)Mounzer Agha · UPMC Hillman Cancer Center6 papers (2021–2025)James N. Kochenderfer · National Institutes of Health6 papers (2018–2023)Lida Pacaud · University College London6 papers (2021–2023)Jacalyn Rosenblatt · Harvard University6 papers (2018–2020)Monica Massaro · Boston Biomedical (United States)6 papers (2018–2019)William Deraedt · Janssen (Belgium)6 papers (2021–2023)