Area of research
Neurology · Physiology
Research interest
Research interests include Neuroinflammation and Neurodegeneration Mechanisms, Alzheimer's disease research and treatments, COVID-19 Clinical Research Studies, and Single-cell and spatial transcriptomics.
CRISPRi-based screen of autism spectrum disorder risk genes in microglia uncovers roles of ADNP in microglia endocytosis and synaptic pruning
Granulin loss of function in human mature brain organoids implicates astrocytes in TDP-43 pathology
A CRISPRi/a platform in human iPSC-derived microglia uncovers regulators of disease states
Reactive astrocytes transduce inflammation in a blood-brain barrier model through a TNF-STAT3 signaling axis and secretion of alpha 1-antichymotrypsin
CRISPRi screens in human iPSC-derived astrocytes elucidate regulators of distinct inflammatory reactive states
Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors
Molecular characterization of selectively vulnerable neurons in Alzheimer’s disease
Genome-wide CRISPRi/a screens in human neurons link lysosomal failure to ferroptosis
Rapid deployment of SARS-CoV-2 testing: The CLIAHUB