Area of research
Cellular and Molecular Neuroscience · Neurology
Research interest
Research interests include Neuroinflammation and Neurodegeneration Mechanisms, Nerve injury and regeneration, Neurogenesis and neuroplasticity mechanisms, and Insect-Plant Interactions and Control.
Derivation and transcriptional reprogramming of border-forming wound repair astrocytes after spinal cord injury or stroke in mice
Reactive astrocytes transduce inflammation in a blood-brain barrier model through a TNF-STAT3 signaling axis and secretion of alpha 1-antichymotrypsin
Divergent transcriptional regulation of astrocyte reactivity across disorders
CRISPRi screens in human iPSC-derived astrocytes elucidate regulators of distinct inflammatory reactive states
Transcription factor network analysis identifies REST/NRSF as an intrinsic regulator of CNS regeneration in mice
Foreign body responses in mouse central nervous system mimic natural wound responses and alter biomaterial functions
Required growth facilitators propel axon regeneration across complete spinal cord injury
Cell-specific and region-specific transcriptomics in the multiple sclerosis model: Focus on astrocytes
Ependymal cell contribution to scar formation after spinal cord injury is minimal, local and dependent on direct ependymal injury
Astrocyte scar formation aids central nervous system axon regeneration
Astrocyte Kir4.1 ion channel deficits contribute to neuronal dysfunction in Huntington's disease model mice
Astrocyte CCL2 sustains immune cell infiltration in chronic experimental autoimmune encephalomyelitis
Heterogeneity of reactive astrocytes
Inflammatory Mediators Alter the Astrocyte Transcriptome and Calcium Signaling Elicited by Multiple G-Protein-Coupled Receptors
Sustained local delivery of bioactive nerve growth factor in the central nervous system via tunable diblock copolypeptide hydrogel depots