Area of research
Hematology · Cardiology and Cardiovascular Medicine
Research interest
Research interests include Platelet Disorders and Treatments, Blood Coagulation and Thrombosis Mechanisms, Antiplatelet Therapy and Cardiovascular Diseases, and Blood properties and coagulation.
Procoagulant off-target effect of the direct oral anticoagulant reversal agent andexanet alfa
Human and mouse platelet transcriptomes and proteomes for phenotyping 3474 genes with hemostatic and platelet traits
Suppressed ORAI1-STIM1-dependent Ca2+ entry by protein kinase C isoforms regulating platelet procoagulant activity
Altered whole blood thrombin generation and hyperresponsive platelets in patients with pancreatic cancer
Endothelium‐mediated regulation of platelet activation: Involvement of multiple protein kinases
Multi-phased Kinetics and Interaction of Protein Kinase Signaling in Glycoprotein VI-Induced Platelet αIIbβ3 Integrin Activation and Degranulation
Consensus report on markers to distinguish procoagulant platelets from apoptotic platelets: communication from the Scientific and Standardization Committee of the ISTH
Platelet glycoprotein V spatio-temporally controls fibrin formation
Crucial roles of red blood cells and platelets in whole blood thrombin generation
Antagonistic Roles of Human Platelet Integrin αIIbβ3 and Chemokines in Regulating Neutrophil Activation and Fate on Arterial Thrombi Under Flow
Differential Regulation of GPVI-Induced Btk and Syk Activation by PKC, PKA and PP2A in Human Platelets
Targeting platelet-derived CXCL12 impedes arterial thrombosis
Molecular Mechanisms of Hemostasis, Thrombosis and Thrombo-Inflammation
Structure-Based Cyclic Glycoprotein Ibα-Derived Peptides Interfering with von Willebrand Factor-Binding, Affecting Platelet Aggregation under Shear
Platelet Activation Mechanisms and Consequences of Immune Thrombocytopenia
Molecular Proteomics and Signalling of Human Platelets in Health and Disease
Platelet-primed interactions of coagulation and anticoagulation pathways in flow-dependent thrombus formation
Native, Intact Glucagon-Like Peptide 1 Is a Natural Suppressor of Thrombus Growth Under Physiological Flow Conditions
Impaired iloprost-induced platelet inhibition and phosphoproteome changes in patients with confirmed pseudohypoparathyroidism type Ia, linked to genetic mutations in GNAS
The Microbiota Promotes Arterial Thrombosis in Low-Density Lipoprotein Receptor-Deficient Mice
Comparative Analysis of Microfluidics Thrombus Formation in Multiple Genetically Modified Mice: Link to Thrombosis and Hemostasis
AMPK-ACC signaling modulates platelet phospholipids and potentiates thrombus formation
High-throughput elucidation of thrombus formation reveals sources of platelet function variability
Platelet heterogeneity in activation-induced glycoprotein shedding: functional effects
Atherothrombosis and Thromboembolism: Position Paper from the Second Maastricht Consensus Conference on Thrombosis
Congenital macrothrombocytopenia with focal myelofibrosis due to mutations in human G6b-B is rescued in humanized mice
Maintenance of murine platelet homeostasis by the kinase Csk and phosphatase CD148
Inhibitory mechanisms of very low–dose rivaroxaban in non–ST-elevation myocardial infarction
Chemokine interactome mapping enables tailored intervention in acute and chronic inflammation
Platelet function is modified by common sequence variation in megakaryocyte super enhancers