Area of research
Hematology · Cardiology and Cardiovascular Medicine
Research interest
Research focused on Platelet and Thrombus, with related work in Platelet activation, GPVI, Fibrin. Notable publications include 'Distinct contributions of complement factors to platelet activation and fibrin formation in venous thrombus development', 'Identification of platelet function defects by multi-parameter assessment of thrombus formation', and 'Gut microbiota regulate hepatic von Willebrand factor synthesis and arterial thrombus formation via Toll-like receptor-2'.
The Diagnostic Assessment of Platelet Function Defects - Part 2: Update on Platelet Disorders
The Diagnostic Assessment of Inherited Platelet Function Defects - Part 1: An Overview of the Diagnostic Approach and Laboratory Methods
Interplay Between Thrombospondin-1 and CD36 Modulates Platelet–RBC Interaction in Thrombosis and Abdominal Aneurysm Formation
Association of Specific Antiphospholipid Antibodies to Platelet Count and Thrombocytopenia
Multi-phased Kinetics and Interaction of Protein Kinase Signaling in Glycoprotein VI-Induced Platelet αIIbβ3 Integrin Activation and Degranulation
First- vs. Second-Generation Autologous Platelet Concentrates and Their Implications for Wound Healing: Differences in Proteome and Secretome
Clinical profile and outcome of isolated pulmonary embolism: a systematic review and meta-analysis
Circulating microRNAs predict recurrence and death following venous thromboembolism
Antagonistic Roles of Human Platelet Integrin αIIbβ3 and Chemokines in Regulating Neutrophil Activation and Fate on Arterial Thrombi Under Flow
A novel von Willebrand factor multimer ratio as marker of disease activity in thrombotic thrombocytopenic purpura
Differential Regulation of GPVI-Induced Btk and Syk Activation by PKC, PKA and PP2A in Human Platelets
Targeting platelet-derived CXCL12 impedes arterial thrombosis
Molecular Mechanisms of Hemostasis, Thrombosis and Thrombo-Inflammation
Structure-Based Cyclic Glycoprotein Ibα-Derived Peptides Interfering with von Willebrand Factor-Binding, Affecting Platelet Aggregation under Shear
Proteomics reveals differential adsorption of angiogenic platelet lysate proteins on calcium phosphate bone substitute materials
Novel GATA1 Variant Causing a Bleeding Phenotype Associated with Combined Platelet α-/δ-Storage Pool Deficiency and Mild Dyserythropoiesis Modified by a SLC4A1 Variant
Soluble Platelet Release Factors as Biomarkers for Cardiovascular Disease
The ISTH bleeding assessment tool as predictor of bleeding events in inherited platelet disorders: Communication from the ISTH SSC Subcommittee on Platelet Physiology
Molecular Proteomics and Signalling of Human Platelets in Health and Disease
Platelet Phenotyping and Function Testing in Thrombocytopenia
Age-Dependent Control of Collagen-Dependent Platelet Responses by Thrombospondin-1—Comparative Analysis of Platelets from Neonates, Children, Adolescents, and Adults
Fine-Tuning of Platelet Responses by Serine/Threonine Protein Kinases and Phosphatases—Just the Beginning
Curcumin at Low Doses Potentiates and at High Doses Inhibits ABT-737-Induced Platelet Apoptosis
Effects of Clopidogrel, Prasugrel and Ticagrelor on Microvascular Function and Platelet Reactivity in Patients With Acute Coronary Syndrome Undergoing Coronary Artery Stenting. A Randomized, Blinded, Parallel Group Trial
Gut Microbiota Restricts NETosis in Acute Mesenteric Ischemia-Reperfusion Injury
The Cell Cycle Checkpoint System MAST(L)-ENSA/ARPP19-PP2A is Targeted by cAMP/PKA and cGMP/PKG in Anucleate Human Platelets
Platelet-Derived GARP Induces Peripheral Regulatory T Cells—Potential Impact on T Cell Suppression in Patients with Melanoma-Associated Thrombocytosis
Reelin Amplifies Glycoprotein VI Activation and AlphaIIb Beta3 Integrin Outside-In Signaling via PLC Gamma 2 and Rho GTPases
The RhoA regulators Myo9b and GEF‐H1 are targets of cyclic nucleotide‐dependent kinases in platelets
CD36‐fibrin interaction propagates FXI‐dependent thrombin generation of human platelets