Area of research
Immunology · Molecular Biology
Research interest
Research interests include Cell death mechanisms and regulation, Galectins and Cancer Biology, Hepatitis B Virus Studies, and Phagocytosis and Immune Regulation.
Chronic stress drives liver cancer by impairing the hepatic kynurenine pathway and immune surveillance.
TIM-3-dependent lysosome biogenesis is required for myelin debris clearance in macrophages.
hnRNPA2B1 induces HBV cccDNA degradation by recruiting APOBEC3B.
Detection of pathogenic novel intronic splicing variants in the <i>KIDINS220</i> gene causes motor developmental delay.
Tim-3 facilitates dendritic cell ferroptosis and impairs anti-tumor immunity in steatohepatitis-related HCC
Chronic stress–induced ANPEP drives liver cancer progression by increasing glutathione synthesis and inhibiting ferroptosis
Palmitoylation of TIM-3 promotes immune exhaustion and restrains antitumor immunity
Palmitoylation of TIM-3 promotes immune exhaustion and restrains antitumor immunity.
VEGFR2 blockade inhibits glioblastoma cell proliferation by enhancing mitochondrial biogenesis
Beta-Cell Tipe1 Orchestrates Insulin Secretion and Cell Proliferation by Promoting Gαs/cAMP Signaling via USP5.
Tim-4 alleviates acute hepatic injury by modulating homeostasis and function of NKT cells.
Cholesterol: A friend to viruses.
Early life gut microbiota sustains liver-resident natural killer cells maturation via the butyrate-IL-18 axis.
Identification of a small-molecule Tim-3 inhibitor to potentiate T cell-mediated antitumor immunotherapy in preclinical mouse models.
TIM-4 orchestrates mitochondrial homeostasis to promote lung cancer progression via ANXA2/PI3K/AKT/OPA1 axis.
ZHX2 emerges as a negative regulator of mitochondrial oxidative phosphorylation during acute liver injury
Transcription factor Zhx2 is a checkpoint that programs macrophage polarization and antitumor response.
ZHX2 emerges as a negative regulator of mitochondrial oxidative phosphorylation during acute liver injury.
T-cell immunoglobulin- and mucin-domain-containing molecule-4 maintains adipose tissue homeostasis by orchestrating M2 macrophage polarization via nuclear factor kappa B pathway.
Peptide targeting the interaction of S protein cysteine-rich domain with Ezrin restricts pan-coronavirus infection.
Upregulation of TIPE1 in tubular epithelial cell aggravates diabetic nephropathy by disrupting PHB2 mediated mitophagy
NAD+ salvage governs mitochondrial metabolism, invigorating natural killer cell antitumor immunity
LINC01431 Promotes Histone H4R3 Methylation to Impede HBV Covalently Closed Circular DNA Transcription by Stabilizing PRMT1
Tim-4 reprograms cholesterol metabolism to suppress antiviral innate immunity by disturbing the Insig1-SCAP interaction in macrophages
Review of: "LKB1 acts as a critical brake for the glucagon-mediated fasting response"
Palmitoylation of SARS-CoV-2 S protein is essential for viral infectivity
Hepatic Macrophage as a Key Player in Fatty Liver Disease
Switch receptor T3/28 improves long-term persistence and antitumor efficacy of CAR-T cells.
Transcription factor Zhx2 restricts NK cell maturation and suppresses their antitumor immunity.
IL‐6 promotes metastasis of non‐small‐cell lung cancer by up‐regulating TIM‐4 via NF‐κB