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Philipp‐Sebastian Koch

Heidelberg University · DE
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Area of research
Hepatology · Molecular Biology
Research interest
Research interests include Liver physiology and pathology, Organ Transplantation Techniques and Outcomes, Protein Tyrosine Phosphatases, and Liver Disease Diagnosis and Treatment.
h-index
21
citations
1,858
works
65
NIH funding
primary concept
email

Recent publications

Steatohepatitis-induced vascular niche alterations promote melanoma metastasis
Cancer & Metabolism 2025cited by 2position: middledoi
Endothelial c-Maf prevents MASLD-like liver fibrosis by regulating chromatin accessibility to suppress pathogenic microvascular cell subsets
JHEP Reports 2025cited by 1position: middledoi
Endothelial cells drive organ fibrosis in mice by inducing expression of the transcription factor SOX9
Science Translational Medicine 2024cited by 52position: middledoi
Activation of Wnt/<b>β</b>-catenin signaling is critical for the tumorigenesis of choroid plexus
Neuro-Oncology 2024cited by 9position: middledoi
Integration of transcriptomics, proteomics and loss-of-function screening reveals WEE1 as a target for combination with dasatinib against proneural glioblastoma
Cancer Letters 2024cited by 7position: middledoi
Liver sinusoidal endothelial cells orchestrate NK cell recruitment and activation in acute inflammatory liver injury
Cell Reports 2023cited by 35position: middledoi
ALK1 controls hepatic vessel formation, angiodiversity, and angiocrine functions in hereditary hemorrhagic telangiectasia of the liver
Hepatology 2022cited by 34position: lastdoi
Lyve-1 deficiency enhances the hepatic immune microenvironment entailing altered susceptibility to melanoma liver metastasis
Cancer Cell International 2022cited by 22position: middledoi
Liver sinusoidal endothelial cells orchestrate NK cell recruitment and activation in acute inflammatory liver injury
bioRxiv (Cold Spring Harbor Laboratory) 2022cited by 7position: middledoi
Angiodiversity and organotypic functions of sinusoidal endothelial cells
Angiogenesis 2021cited by 102position: firstdoi
Bone marrow sinusoidal endothelium controls terminal erythroid differentiation and reticulocyte maturation
Nature Communications 2021cited by 19position: lastdoi
Single-Cell RNA Sequencing of Tumor-Infiltrating NK Cells Reveals that Inhibition of Transcription Factor HIF-1α Unleashes NK Cell Activity
Immunity 2020cited by 329position: middledoi
Endothelial GATA4 controls liver fibrosis and regeneration by preventing a pathogenic switch in angiocrine signaling
Journal of Hepatology 2020cited by 171position: middledoi
Reconstruction of Nasal Defects With Dermal Skin Substitutes—A Retrospective Study of 36 Defects
Journal of Cutaneous Medicine and Surgery 2019cited by 13position: middledoi
Reconstruction of defects of the proximal nasal sidewall using the procerus perforator flap
JDDG Journal der Deutschen Dermatologischen Gesellschaft 2019cited by 7position: middledoi
Rekonstruktion eines Defektes am proximalen Nasenabhang mittels Procerus‐Insellappenplastik
JDDG Journal der Deutschen Dermatologischen Gesellschaft 2019cited by 0position: middledoi
GATA4-dependent organ-specific endothelial differentiation controls liver development and embryonic hematopoiesis
Journal of Clinical Investigation 2017cited by 171position: middledoi
Angiocrine Wnt signaling controls liver growth and metabolic maturation in mice
Hepatology 2017cited by 115position: lastdoi
Angiocrine Bmp2 signaling in murine liver controls normal iron homeostasis
Blood 2016cited by 163position: firstdoi
Endothelial transdifferentiation in hepatocellular carcinoma: loss of Stabilin‐2 expression in peri‐tumourous liver correlates with increased survival
Liver International 2013cited by 67position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Sergij Goerdt · Heidelberg University10 papers (2013–2025)Kai Schledzewski · University Hospital Heidelberg9 papers (2013–2025)Cyrill Géraud · University Hospital Heidelberg8 papers (2013–2025)Carsten Sticht · Medizinische Fakultät Mannheim7 papers (2016–2025)Victor Olsavszky · University Hospital Heidelberg7 papers (2016–2025)Manuel Winkler · University Hospital Heidelberg5 papers (2020–2025)Hellmut G. Augustin · Heidelberg Engineering (Germany)4 papers (2013–2021)Sina W. Kürschner · University Hospital Heidelberg4 papers (2020–2025)Adelheid Cerwenka · University of Mannheim4 papers (2020–2023)Christian David Schmid · University Hospital Heidelberg4 papers (2020–2025)Carolin Mogler · Tumaini University4 papers (2013–2023)Ana Stojanovic · University of Mannheim4 papers (2020–2023)Bernd Arnold · German Cancer Research Center3 papers (2013–2017)Sebastian A. Wohlfeil · German Cancer Research Center3 papers (2017–2025)Johannes Benecke · University Hospital Heidelberg3 papers (2019–2019)Corinne Bauer · Medizinische Fakultät Mannheim3 papers (2019–2019)Theresa Staniczek · University Hospital Heidelberg3 papers (2020–2025)Johanna Zierow · University Hospital Heidelberg3 papers (2016–2017)Johannes Hoffmann · Ludwig-Maximilians-Universität München3 papers (2022–2025)Karsten Richter · Heidelberg University3 papers (2017–2025)
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