Area of research
Molecular Biology · Hematology
Research interest
Research interests include Bioinformatics and Genomic Networks, Gene expression and cancer classification, Biomedical Text Mining and Ontologies, and Acute Myeloid Leukemia Research.
Proteomic Portrait of Degranulation Program in Human Circulating Neutrophils Upon Multi-Inflammatory and Infectious Activation
Artificial intelligence in precision mRNA therapeutics: Towards genomic language models and multi-agent virtual humans
VAM: A Multimodal Dynamical Foundation Model for Characterizing Human Aging Dynamics and Enabling Virtual Aging Perturbation
Network-phenotype key gene screening (NPKG) identifies therapeutically relevant targets for neurodegenerative diseases
CD4+ tissue-resident memory Th17 cells are a major source of IL-17A in Spondyloarthritis synovial tissue
A computational medicine framework integrating multi-omics, systems biology, and artificial neural networks for Alzheimer's disease therapeutic discovery
HemaScope: A Tool for Analyzing Single-cell and Spatial Transcriptomics Data of Hematopoietic Cells.
Resolving Leukemia Heterogeneity and Lineage Aberrations with HematoMap.
Metabolomic insights into pathogenesis and therapeutic potential in adult acute lymphoblastic leukemia.
Multidimensional tumor-blood profiling uncovers systemic lymphocyte-monocyte imbalance in pituitary neuroendocrine tumors.
Prospective observational study on biomarkers of response in pancreatic ductal adenocarcinoma.
The impact of age and number of mutations on the size of clonal hematopoiesis.
Aging and comprehensive molecular profiling in acute myeloid leukemia.
Cellular hierarchy insights reveal leukemic stem-like cells and early death risk in acute promyelocytic leukemia.
Phase separation of PML/RARα and BRD4 coassembled microspeckles governs transcriptional dysregulation in acute promyelocytic leukemia.
A cross-disease, pleiotropy-driven approach for therapeutic target prioritization and evaluation.
Priority index for critical Covid-19 identifies clinically actionable targets and drugs.
Loss of heterozygosity exploited for collateral lethality-based cancer therapy.
Diverse rescue potencies of p53 mutations to ATO are predetermined by intrinsic mutational properties.
OpenXGR: a web-server update for genomic summary data interpretation.
Priority index for asthma (PIA): In silico discovery of shared and distinct drug targets for adult- and childhood-onset disease
Trained immunity in human monocyte enhances myeloid-T-cell pathogenic crosstalk in Ankylosing Spondylitis
Multimodule characterization of immune subgroups in intrahepatic cholangiocarcinoma reveals distinct therapeutic vulnerabilities
Transcriptome-wide subtyping of pediatric and adult T cell acute lymphoblastic leukemia in an international study of 707 cases
Priority index: database of genetic targets in immune-mediated disease.
Identification of a novel GR-ARID1a-P53BP1 protein complex involved in DNA damage repair and cell cycle regulation.
PiER: web-based facilities tailored for genetic target prioritisation harnessing human disease genetics, functional genomics and protein interactions.
A PML/RARα direct target atlas redefines transcriptional deregulation in acute promyelocytic leukemia.
Identification of copy number variation-driven molecular subtypes informative for prognosis and treatment in pancreatic adenocarcinoma of a Chinese cohort
Genomic Insights into Myasthenia Gravis Identify Distinct Immunological Mechanisms in Early and Late Onset Disease.