Area of research
Hematology · Public Health, Environmental and Occupational Health
Research interest
Research interests include Acute Myeloid Leukemia Research, Acute Lymphoblastic Leukemia research, Cancer-related molecular mechanisms research, and Bioinformatics and Genomic Networks.
Molecular insight into the interplay among heterogeneous plasmacytes and microenvironment cells and their clinical relevance in myeloma.
Targeting ZMIZ1 induces differentiation in acute myeloid leukemia via chromatin remodeling.
HSCs/MPPs as cells of origin with altered differentiation hierarchy impairing immunomicroenvironment in <i>PML::RARA</i> and <i>CBFα/β</i> fusion AML.
A novel nanobody-based TCR-like CAR-T therapy targeting PRAME for the treatment of acute myeloid leukemia.
Targeting RBPMS selectively eliminates FOXO1-mediated stem cell signatures in mouse models of acute myeloid leukemia.
VAM: A Multimodal Dynamical Foundation Model for Characterizing Human Aging Dynamics and Enabling Virtual Aging Perturbation
Indole-3 propionate inhibits NF-κB/NLRP3-mediated osteoclastogenesis and improves bone quality in high-fat-diet induced obese mice
Incidence, mortality, and survival associated with acute leukaemia subtypes by age group in China: a population-based cancer registry analysis and cohort study.
HemaScope: A Tool for Analyzing Single-cell and Spatial Transcriptomics Data of Hematopoietic Cells.
Indoleamine 2,3-dioxygenase 1 alters the proportions of B cell subpopulations in the microenvironment of acute myeloid leukemia.
ggalign: Bridging the Grammar of Graphics and Biological Multilayered Complexity.
Resolving Leukemia Heterogeneity and Lineage Aberrations with HematoMap.
Proteomic subtypes enrich current acute myeloid leukemia nomenclature and reflect intrinsic pathogenesis alongside aging.
KMT2A alterations in acute myeloid leukemia: a proposed genetic risk model and transplantation outcomes.
ggalign: Bridging the Grammar of Graphics and Biological Multilayered Complexity
Differences in response to immunotherapy drugs including blinatumomab and inotuzumab ozogamicin in B-ALL patients.
Molecular mechanisms of unique therapeutic potential of CUDC-907 for MEF2D fusion-driven BCP-ALL.
Neutrophil activation and clonal CAR-T re-expansion underpinning cytokine release syndrome during ciltacabtagene autoleucel therapy in multiple myeloma.
The landscape of NUP98 rearrangements clinical characteristics and treatment response from 1491 acute leukemia patients.
The impact of age and number of mutations on the size of clonal hematopoiesis.
Aging and comprehensive molecular profiling in acute myeloid leukemia.
Facilitating integrative and personalized oncology omics analysis with UCSCXenaShiny
TCCIA: a comprehensive resource for exploring CircRNA in cancer immunotherapy.
Facilitating integrative and personalized oncology omics analysis with UCSCXenaShiny.
<i>PICALM::MLLT10</i> may indicate a new subgroup of acute leukemias with miscellaneous immunophenotype and poor initial treatment response but showing sensitivity to venetoclax.
Refined risk stratification helps guiding transplantation choice in adult BCR::ABL1-positive acute lymphoblastic leukemia.
Correlation of serum cotinine with fatty liver index in adults: data from the NHANES March 2017 and 2018
CSF3R P733T is a deleterious germline variant in acute leukaemia showing gain-of-function-like T618I mutation.
NAD metabolism-related genes provide prognostic value and potential therapeutic insights for acute myeloid leukemia.
GENETIC INSIGHTS INTO SEPSIS: MENDELIAN RANDOMIZATION ANALYSIS OF CEREBROSPINAL FLUID METABOLITES