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Pavla Fajtová

University of California San Diego · US
Area of research
Molecular Biology · Parasitology
Research interest
Research interests include Parasites and Host Interactions, SARS-CoV-2 and COVID-19 Research, Advanced biosensing and bioanalysis techniques, and Ubiquitin and proteasome pathways.
h-index
20
citations
1,203
works
66
NIH funding
primary concept
email

Recent publications

Large library docking for novel <scp>SARS‐CoV</scp> ‐2 main protease non‐covalent and covalent inhibitors
Protein Science 2023cited by 42position: middledoi
Empirical Optimization of Peptide Sequence and Nanoparticle Colloidal Stability: The Impact of Surface Ligands and Implications for Colorimetric Sensing
ACS Applied Materials & Interfaces 2023cited by 21position: middledoi
Endoproteolysis of Oligopeptide-Based Coacervates for Enzymatic Modeling
ACS Nano 2023cited by 16position: middledoi
Native metabolomics identifies the rivulariapeptolide family of protease inhibitors
Nature Communications 2022cited by 47position: middledoi
Structure-Based Identification of Naphthoquinones and Derivatives as Novel Inhibitors of Main Protease M <sup>pro</sup> and Papain-like Protease PL <sup>pro</sup> of SARS-CoV-2
Journal of Chemical Information and Modeling 2022cited by 43position: middledoi
Protease-Responsive Peptide-Conjugated Mitochondrial-Targeting AIEgens for Selective Imaging and Inhibition of SARS-CoV-2-Infected Cells
ACS Nano 2022cited by 43position: middledoi
Peptide Amphiphile Mediated Co‐assembly for Nanoplasmonic Sensing
Angewandte Chemie International Edition 2022cited by 30position: middledoi
A Clinical-Stage Cysteine Protease Inhibitor blocks SARS-CoV-2 Infection of Human and Monkey Cells
ACS Chemical Biology 2021cited by 120position: middledoi
Potent Anti-SARS-CoV-2 Activity by the Natural Product Gallinamide A and Analogues via Inhibition of Cathepsin L
Journal of Medicinal Chemistry 2021cited by 84position: middledoi
A Charge‐Switchable Zwitterionic Peptide for Rapid Detection of SARS‐CoV‐2 Main Protease
Angewandte Chemie International Edition 2021cited by 75position: middledoi
A Dual‐Color Fluorescent Probe Allows Simultaneous Imaging of Main and Papain‐like Proteases of SARS‐CoV‐2‐Infected Cells for Accurate Detection and Rapid Inhibitor Screening
Angewandte Chemie International Edition 2021cited by 48position: middledoi
Activatable Carbocyanine Dimers for Photoacoustic and Fluorescent Detection of Protease Activity
ACS Sensors 2021cited by 40position: middledoi
SmSP2: A serine protease secreted by the blood fluke pathogen Schistosoma mansoni with anti-hemostatic properties
PLoS neglected tropical diseases 2018cited by 53position: middledoi
Excretion/secretion products from Schistosoma mansoni adults, eggs and schistosomula have unique peptidase specificity profiles
Biochimie 2015cited by 56position: middledoi
Trypsin- and Chymotrypsin-Like Serine Proteases in Schistosoma mansoni – ‘The Undiscovered Country’
PLoS neglected tropical diseases 2014cited by 55position: middledoi
Activation Route of the Schistosoma mansoni Cathepsin B1 Drug Target: Structural Map with a Glycosaminoglycan Switch
Structure 2014cited by 53position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Anthony J. O’Donoghue · University of California San Diego11 papers (2015–2023)Jesse V. Jokerst · University of California San Diego7 papers (2021–2023)Zhicheng Jin · University of San Diego6 papers (2021–2023)Wonjun Yim · Massachusetts Institute of Technology5 papers (2021–2023)Jiajing Zhou · University of San Diego5 papers (2021–2023)Yong Cheng · Chinese Academy of Sciences5 papers (2021–2023)Conor R. Caffrey · University of California San Diego4 papers (2014–2018) · 4 papers (2014–2018)James H. McKerrow · University of California San Diego4 papers (2014–2022)Raina M. Borum · Amgen (United States)4 papers (2021–2022)Tengyu He · University of California San Diego4 papers (2021–2023)Ming Xu · Fudan University4 papers (2021–2022) · 4 papers (2014–2018)Matthew N. Creyer · University of California San Diego3 papers (2021–2022)Justin Yeung · University of California San Diego3 papers (2022–2023) · 3 papers (2014–2018) · 3 papers (2014–2018) · 3 papers (2014–2018)Maurice Retout · University of California San Diego3 papers (2021–2023)Colman Moore · Merck & Co., Inc., Rahway, NJ, USA (United States)3 papers (2021–2021)