Area of research
Infectious Diseases · Molecular Biology
Research interest
Research interests include Biology, Pichia pastoris, Computational biology, Gene, Recombinant DNA, and CRISPR.
Deletion of low-essentiality, secretion-associated genes enhances recombinant protein production in Komagataella phaffii
Vaccine targeting to mucosal lymphoid tissues promotes humoral immunity in the gastrointestinal tract
CRISPR-Cas9 knockout screen informs efficient reduction of the Komagataella phaffii secretome
Intranasal vaccination with lipid-conjugated immunogens promotes antigen transmucosal uptake to drive mucosal and systemic immunity
SARS-CoV-2 receptor binding domain displayed on HBsAg virus–like particles elicits protective immunity in macaques
Steric accessibility of the N-terminus improves the titer and quality of recombinant proteins secreted from Komagataella phaffii
Engineered SARS-CoV-2 receptor binding domain improves manufacturability in yeast and immunogenicity in mice
Phosphate-mediated coanchoring of RBD immunogens and molecular adjuvants to alum potentiates humoral immunity against SARS-CoV-2
Simplified Gene Knockout by CRISPR-Cas9-Induced Homologous Recombination
Molecular engineering improves antigen quality and enables integrated manufacturing of a trivalent subunit vaccine candidate for rotavirus
Identifying Improved Sites for Heterologous Gene Integration Using ATAC-seq
Host-Informed Expression of CRISPR Guide RNA for Genomic Engineering in <i>Komagataella phaffii</i>
Comparative genome‐scale analysis of <i>Pichia pastoris</i> variants informs selection of an optimal base strain
On-demand manufacturing of clinical-quality biopharmaceuticals
The yeast stands alone: the future of protein biologic production