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В. В. Бредер

Russian Cancer Research Center NN Blokhin · RU
Area of research
Hepatology · Oncology
Research interest
Research interests include Hepatocellular Carcinoma Treatment and Prognosis, Cancer Immunotherapy and Biomarkers, Lung Cancer Treatments and Mutations, and Liver Disease Diagnosis and Treatment.
h-index
32
citations
21,204
works
241
NIH funding
primary concept
Medicine
email

Recent publications

Adjuvant pembrolizumab for participants with hepatocellular carcinoma and complete radiologic response after surgical resection or local ablation: The phase 3 keynote-937 study.
Journal of Clinical Oncology 2026cited by 5position: middledoi
Durvalumab with or without bevacizumab with transarterial chemoembolisation in hepatocellular carcinoma (EMERALD-1): a multiregional, randomised, double-blind, placebo-controlled, phase 3 study
The Lancet 2025cited by 206position: middledoi
Five-year overall survival update from the HIMALAYA study of tremelimumab plus durvalumab in unresectable HCC
Journal of Hepatology 2025cited by 92position: middledoi
A phase III randomized study of first-line NUC-1031/cisplatin vs. gemcitabine/cisplatin in advanced biliary tract cancer
Journal of Hepatology 2025cited by 9position: middledoi
Four-year overall survival update from the phase III HIMALAYA study of tremelimumab plus durvalumab in unresectable hepatocellular carcinoma
Annals of Oncology 2024cited by 292position: middledoi
Durvalumab or placebo plus gemcitabine and cisplatin in participants with advanced biliary tract cancer (TOPAZ-1): updated overall survival from a randomised phase 3 study
˜The œLancet. Gastroenterology & hepatology 2024cited by 235position: middledoi
Durvalumab plus gemcitabine and cisplatin in advanced biliary tract cancer (TOPAZ-1): patient-reported outcomes from a randomised, double-blind, placebo-controlled, phase 3 trial
The Lancet Oncology 2024cited by 130position: middledoi
Efficacy and Safety of Atezolizumab plus Bevacizumab versus Sorafenib in Hepatocellular Carcinoma with Main Trunk and/or Contralateral Portal Vein Invasion in IMbrave150
Liver Cancer 2024cited by 28position: lastdoi
947MO Five-year overall survival (OS) and OS by tumour response measures from the phase III HIMALAYA study of tremelimumab plus durvalumab in unresectable hepatocellular carcinoma (uHCC)
Annals of Oncology 2024cited by 24position: middledoi
Four-year outcomes and circulating tumor DNA (ctDNA) analysis of pembrolizumab (pembro) plus concurrent chemoradiation therapy (cCRT) in unresectable, locally advanced, stage III non–small-cell lung cancer (NSCLC): From KEYNOTE-799.
Journal of Clinical Oncology 2024cited by 5position: middledoi
Lenvatinib plus pembrolizumab versus lenvatinib plus placebo for advanced hepatocellular carcinoma (LEAP-002): a randomised, double-blind, phase 3 trial
The Lancet Oncology 2023cited by 408position: middledoi
Pembrolizumab as Second-Line Therapy for Advanced Hepatocellular Carcinoma: Longer Term Follow-Up from the Phase 3 KEYNOTE-240 Trial
Liver Cancer 2023cited by 44position: middledoi
SO-15 Four-year overall survival update from the phase 3 HIMALAYA study of tremelimumab plus durvalumab in unresectable hepatocellular carcinoma
Annals of Oncology 2023cited by 21position: middledoi
Plain language summary of the HIMALAYA study: tremelimumab and durvalumab for unresectable hepatocellular carcinoma (liver cancer)
Future Oncology 2023cited by 16position: middledoi
Tremelimumab plus Durvalumab in Unresectable Hepatocellular Carcinoma
NEJM Evidence 2022cited by 1,386position: middledoi
Cabozantinib plus atezolizumab versus sorafenib for advanced hepatocellular carcinoma (COSMIC-312): a multicentre, open-label, randomised, phase 3 trial
The Lancet Oncology 2022cited by 514position: middledoi
Phase 3 randomized, open-label, multicenter study of tremelimumab (T) and durvalumab (D) as first-line therapy in patients (pts) with unresectable hepatocellular carcinoma (uHCC): HIMALAYA.
Journal of Clinical Oncology 2022cited by 397position: middledoi
Two-year update from KEYNOTE-799: Pembrolizumab plus concurrent chemoradiation therapy (cCRT) for unresectable, locally advanced, stage III NSCLC.
Journal of Clinical Oncology 2022cited by 30position: middledoi
Patient-reported outcomes for the phase 3 TOPAZ-1 study of durvalumab plus gemcitabine and cisplatin in advanced biliary tract cancer.
Journal of Clinical Oncology 2022cited by 15position: middledoi
Updated efficacy and safety data from IMbrave150: Atezolizumab plus bevacizumab vs. sorafenib for unresectable hepatocellular carcinoma
Journal of Hepatology 2021cited by 1,581position: middledoi
Patient-reported outcomes with atezolizumab plus bevacizumab versus sorafenib in patients with unresectable hepatocellular carcinoma (IMbrave150): an open-label, randomised, phase 3 trial
The Lancet Oncology 2021cited by 372position: middledoi
IMbrave150: Updated overall survival (OS) data from a global, randomized, open-label phase III study of atezolizumab (atezo) + bevacizumab (bev) versus sorafenib (sor) in patients (pts) with unresectable hepatocellular carcinoma (HCC).
Journal of Clinical Oncology 2021cited by 318position: middledoi
Pembrolizumab Plus Concurrent Chemoradiation Therapy in Patients With Unresectable, Locally Advanced, Stage III Non–Small Cell Lung Cancer
JAMA Oncology 2021cited by 250position: middledoi
IMbrave150: Exploratory efficacy and safety results of hepatocellular carcinoma (HCC) patients (pts) with main trunk and/or contralateral portal vein invasion (Vp4) treated with atezolizumab (atezo) + bevacizumab (bev) versus sorafenib (sor) in a global Ph III study.
Journal of Clinical Oncology 2021cited by 68position: firstdoi
KEYNOTE-799: Phase 2 trial of pembrolizumab plus platinum chemotherapy and radiotherapy for unresectable, locally advanced, stage 3 NSCLC.
Journal of Clinical Oncology 2021cited by 16position: middledoi
Abstract CT009: IMbrave150: Updated efficacy and safety by risk status in patients (pts) receiving atezolizumab (atezo) + bevacizumab (bev) vs sorafenib (sor) as first-line treatment for unresectable hepatocellular carcinoma (HCC)
Cancer Research 2021cited by 16position: middledoi
Atezolizumab plus Bevacizumab in Unresectable Hepatocellular Carcinoma
New England Journal of Medicine 2020cited by 7,096position: middledoi
Patient-reported outcomes (PROs) from the Phase III IMbrave150 trial of atezolizumab (atezo) + bevacizumab (bev) vs sorafenib (sor) as first-line treatment (tx) for patients (pts) with unresectable hepatocellular carcinoma (HCC).
Journal of Clinical Oncology 2020cited by 35position: middledoi
Phase II study of pembrolizumab (pembro) plus platinum doublet chemotherapy and radiotherapy as first-line therapy for unresectable, locally advanced stage III NSCLC: KEYNOTE-799.
Journal of Clinical Oncology 2020cited by 16position: middledoi
Complete responses (CR) in patients receiving atezolizumab (atezo) + bevacizumab (bev) versus sorafenib (sor) in IMbrave150: A phase III clinical trial for unresectable hepatocellular carcinoma (HCC).
Journal of Clinical Oncology 2020cited by 10position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Ann‐Lii Cheng · Xi'an Jiaotong University16 papers (2016–2024)Masatoshi Kudo · Kindai University15 papers (2016–2023)Philippe Merle · Université Claude Bernard Lyon 115 papers (2016–2024)Richard S. Finn · United States Olympic & Paralympic Committee14 papers (2016–2024)Peter R. Galle · University of Lübeck12 papers (2019–2024)Andrew X. Zhu · Weill Cornell Medicine11 papers (2019–2021)Ho Yeong Lim · New Generation University College11 papers (2019–2023)Michel Ducreux · Inserm10 papers (2019–2024)Masafumi Ikeda · National Cancer Center Hospital East9 papers (2019–2021)Daneng Li · City Of Hope National Medical Center9 papers (2020–2024)Ahmed O. Kaseb · The University of Texas MD Anderson Cancer Center9 papers (2019–2022)Wendy Verret · Gilead Sciences (Spain)8 papers (2019–2021)Stephen L. Chan · California Pacific Medical Center7 papers (2019–2026)Shukui Qin · Affiliated Hospital of Southwest Medical University6 papers (2016–2021)Sairy Hernandez · Research Institute Hospital 12 de Octubre6 papers (2019–2024)Tae‐You Kim · Seoul National University Hospital6 papers (2020–2021)Salma K. Jabbour · Rutgers, The State University of New Jersey5 papers (2020–2024)Dariusz M. Kowalski · National Institute of Oncology5 papers (2020–2024)Noemı́ Reguart · Hospital Clínic de Barcelona5 papers (2020–2024)Baerin Houghton · Port Macquarie Base Hospital5 papers (2020–2024)