Area of research
Molecular Biology · Oncology
Research interest
Research interests include Genomics and Chromatin Dynamics, Chromatin Remodeling and Cancer, Peptidase Inhibition and Analysis, and Histone Deacetylase Inhibitors Research.
FoxA1/2-dependent epigenomic reprogramming drives lineage switching in lung adenocarcinoma
Structure and functional determinants of Rad6–Bre1 subunits in the histone H2B ubiquitin-conjugating complex
FoxA1 and FoxA2 control growth and cellular identity in NKX2-1-positive lung adenocarcinoma
Chromosome 10q26–driven age-related macular degeneration is associated with reduced levels of <i>HTRA1</i> in human retinal pigment epithelium
Cancer-Associated Gain-of-Function Mutations Activate a SWI/SNF-Family Regulatory Hub
Specialization of the chromatin remodeler RSC to mobilize partially-unwrapped nucleosomes
Targeted deletion of Tcf7l2 in adipocytes promotes adipocyte hypertrophy and impaired glucose metabolism
A novel SH2 recognition mechanism recruits Spt6 to the doubly phosphorylated RNA polymerase II linker at sites of transcription
Regulation of DNA Translocation Efficiency within the Chromatin Remodeler RSC/Sth1 Potentiates Nucleosome Sliding and Ejection
Counteracting H3K4 methylation modulators Set1 and Jhd2 co-regulate chromatin dynamics and gene transcription
The chromatin remodelers RSC and ISW1 display functional and chromatin-based promoter antagonism
Interaction of the Jhd2 Histone H3 Lys-4 Demethylase with Chromatin Is Controlled by Histone H2A Surfaces and Restricted by H2B Ubiquitination
Reprogramming the Maternal Zebrafish Genome after Fertilization to Match the Paternal Methylation Pattern
Germline epigenetics, and reprogramming in zebrafish early embryos