Area of research
Molecular Biology · Public Health, Environmental and Occupational Health
Research interest
Research interests include Genomics and Chromatin Dynamics, Epigenetics and DNA Methylation, Chromatin Remodeling and Cancer, and Acute Lymphoblastic Leukemia research.
Conserved shifts in sperm small non-coding RNA profiles during mouse and human aging
Single-cell transcriptomic atlas of the human testis across the reproductive lifespan
ZBTB16/PLZF regulates juvenile spermatogonial stem cell development through an extensive transcription factor poising network
A Single‐Cell Transcriptome Atlas Characterizes the Immune Landscape of Human Testes During Aging
Single-cell analysis of the developing human ovary defines distinct insights into ovarian somatic and germline progenitors
Multiple repeat regions within mouse DUX recruit chromatin regulators to facilitate an embryonic gene expression program
Single-cell analysis of human testis aging and correlation with elevated body mass index
Establishment of developmental gene silencing by ordered polycomb complex recruitment in early zebrafish embryos
When spermatogenesis meets human aging and elevated body mass
PANDORA-seq expands the repertoire of regulatory small RNAs by overcoming RNA modifications
Single-cell analysis of the developing human testis reveals somatic niche cell specification and fetal germline stem cell establishment
Dissecting mammalian spermatogenesis using spatial transcriptomics
p53 convergently activates Dux/DUX4 in embryonic stem cells and in facioscapulohumeral muscular dystrophy cell models
A Role for SMARCB1 in Synovial Sarcomagenesis Reveals That SS18–SSX Induces Canonical BAF Destruction
Germ cell differentiation requires Tdrd7-dependent chromatin and transcriptome reprogramming marked by germ plasm relocalization
Author Correction: PANDORA-seq expands the repertoire of regulatory small RNAs by overcoming RNA modifications
The Dynamic Transcriptional Cell Atlas of Testis Development during Human Puberty
Cisplatin and carboplatin result in similar gonadotoxicity in immature human testis with implications for fertility preservation in childhood cancer
Cancer-Associated Gain-of-Function Mutations Activate a SWI/SNF-Family Regulatory Hub
Specialization of the chromatin remodeler RSC to mobilize partially-unwrapped nucleosomes
NRF2 loss recapitulates heritable impacts of paternal cigarette smoke exposure
Developmentally Programmed Tankyrase Activity Upregulates β-Catenin and Licenses Progression of Embryonic Genome Activation
Transcriptome-wide profiling of multiple RNA modifications simultaneously at single-base resolution
Maintenance of spatial gene expression by Polycomb-mediated repression after formation of a vertebrate body plan
Isolation and Enrichment of Spermatogonial Stem Cells From Human Testis Tissues
The adult human testis transcriptional cell atlas
Placeholder Nucleosomes Underlie Germline-to-Embryo DNA Methylation Reprogramming
Paternal germ line aging: DNA methylation age prediction from human sperm
Mechanisms of action and regulation of ATP-dependent chromatin-remodelling complexes
Conserved roles of mouse DUX and human DUX4 in activating cleavage-stage genes and MERVL/HERVL retrotransposons