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Zachary A. Knight

Howard Hughes Medical Institute · US
Area of research
Molecular Biology · Genetics
Research interest
Research interests include PI3K/AKT/mTOR signaling in cancer, Chronic Lymphocytic Leukemia Research, Regulation of Appetite and Obesity, and Biochemical Analysis and Sensing Techniques.
h-index
54
citations
15,180
works
146
NIH funding
primary concept
email

Recent publications

Cellular coding of ingestion in the caudal brainstem
bioRxiv (Cold Spring Harbor Laboratory) 2025cited by 0position: lastdoi
Negative feedback control of hypothalamic feeding circuits by the taste of food
Neuron 2024cited by 25position: lastdoi
A subcortical feeding circuit linking an interoceptive node to jaw movement
Nature 2024cited by 23position: middledoi
The neurobiology of thirst and salt appetite
Neuron 2024cited by 12position: lastdoi
Sequential appetite suppression by oral and visceral feedback to the brainstem
Nature 2023cited by 84position: lastdoi
Interoception: Spinal sensory neurons that innervate the intestines
Current Biology 2023cited by 4position: lastdoi
Dopamine subsystems that track internal states
Nature 2022cited by 140position: lastdoi
Enteroendocrine cell types that drive food reward and aversion
eLife 2022cited by 65position: lastdoi
Breaking down a gut-to-brain circuit that prevents malabsorption
Cell 2022cited by 9position: lastdoi
Obesity causes selective and long-lasting desensitization of AgRP neurons to dietary fat
eLife 2020cited by 122position: lastdoi
Soma-Targeted Imaging of Neural Circuits by Ribosome Tethering
Neuron 2020cited by 84position: middledoi
Layers of signals that regulate appetite
Current Opinion in Neurobiology 2020cited by 46position: lastdoi
Genetic Identification of Vagal Sensory Neurons That Control Feeding
Cell 2019cited by 484position: lastdoi
A gut-to-brain signal of fluid osmolarity controls thirst satiation
Nature 2019cited by 139position: lastdoi
Sustained NPY signaling enables AgRP neurons to drive feeding
eLife 2019cited by 137position: lastdoi
Regulation of Body Temperature by the Nervous System
Neuron 2018cited by 768position: lastdoi
Identification of preoptic sleep neurons using retrograde labelling and gene profiling
Nature 2017cited by 324position: middledoi
Dynamics of Gut-Brain Communication Underlying Hunger
Neuron 2017cited by 293position: lastdoi
Neural circuits underlying thirst and fluid homeostasis
Nature reviews. Neuroscience 2017cited by 264position: lastdoi
The Forebrain Thirst Circuit Drives Drinking through Negative Reinforcement
Neuron 2017cited by 137position: lastdoi
Warm-Sensitive Neurons that Control Body Temperature
Cell 2016cited by 406position: lastdoi
Thirst neurons anticipate the homeostatic consequences of eating and drinking
Nature 2016cited by 286position: lastdoi
Hunger neurons drive feeding through a sustained, positive reinforcement signal
eLife 2016cited by 196position: lastdoi
Thirst
Current Biology 2016cited by 135position: lastdoi
Making sense of the sensory regulation of hunger neurons
BioEssays 2016cited by 83position: lastdoi
Sensory Detection of Food Rapidly Modulates Arcuate Feeding Circuits
Cell 2015cited by 663position: lastdoi
Molecular Profiling of Neurons Based on Connectivity
Cell 2014cited by 149position: middledoi
A critical role for mTORC1 in erythropoiesis and anemia
eLife 2014cited by 92position: firstdoi
Ablation of AgRP neurons impairs adaption to restricted feeding
Molecular Metabolism 2014cited by 66position: middledoi
Molecular Profiling of Activated Neurons by Phosphorylated Ribosome Capture
Cell 2012cited by 336position: firstdoi

Grants

No grants ingested yet.

Frequent collaborators

Yiming Chen · Guangzhou University of Chinese Medicine11 papers (2015–2020)Christopher A Zimmerman · Princeton University8 papers (2016–2020)Yen‐Chu Lin · National Yang Ming Chiao Tung University8 papers (2015–2020)Jamie S. Ahn · Howard Hughes Medical Institute6 papers (2017–2022)David E. Leib · Drexel University Elkins Park Campus6 papers (2016–2020)Jeffrey M. Friedman · Howard Hughes Medical Institute5 papers (2012–2024)Truong Ly · Palo Alto University5 papers (2022–2025)Chan Lek Tan · Rockefeller University5 papers (2016–2019)Nilla Sivakumar · University of California, San Francisco5 papers (2022–2025)Lisa R. Beutler · Northwestern University4 papers (2017–2020)James C. R. Grove · Howard Hughes Medical Institute4 papers (2022–2025)Timothy V. Corpuz · Saint Louis University4 papers (2019–2022)Erica L. Huey · Howard Hughes Medical Institute4 papers (2016–2019)Rachel Essner · Beth Israel Deaconess Medical Center4 papers (2016–2020)Ling Bai · Nanjing University of Chinese Medicine4 papers (2019–2022)Seher Kosar · University of Zurich4 papers (2019–2020)Brooke C. Jarvie · Howard Hughes Medical Institute3 papers (2022–2023)Keith Tan · Rockefeller University3 papers (2012–2014)Lindsay Gray · Inscopix (United States)3 papers (2019–2024)Naymalis La Santa Medina · University of California, San Francisco3 papers (2022–2024)