Area of research
Immunology · Infectious Diseases
Research interest
Research interests include interferon and immune responses, Immune Response and Inflammation, Inflammasome and immune disorders, and SARS-CoV-2 and COVID-19 Research.
TRIM23 mediates cGAS-induced autophagy in anti-HSV defense
Publisher Correction: TRIM23 mediates cGAS-induced autophagy in anti-HSV defense
Inherited C-terminal TREX1 variants disrupt homology-directed repair to cause senescence and DNA damage phenotypes in Drosophila, mice, and humans
Spike and nsp6 are key determinants of SARS-CoV-2 Omicron BA.1 attenuation
Acetylation of the NS3 helicase by KAT5γ is essential for flavivirus replication
Virology under the Microscope—a Call for Rational Discourse
Actin cytoskeleton remodeling primes RIG-I-like receptor activation
<i>GTF3A</i> mutations predispose to herpes simplex encephalitis by disrupting biogenesis of the host-derived RIG-I ligand <i>RNA5SP141</i>
ISG15-dependent activation of the sensor MDA5 is antagonized by the SARS-CoV-2 papain-like protease to evade host innate immunity
High-throughput RNA sequencing of paraformaldehyde-fixed single cells
The Small t Antigen of JC Virus Antagonizes RIG-I-Mediated Innate Immunity by Inhibiting TRIM25’s RNA Binding Ability
The herpesvirus accessory protein γ134.5 facilitates viral replication by disabling mitochondrial translocation of RIG-I
Herpesvirus-mediated stabilization of ICP0 expression neutralizes restriction by TRIM23
Nonsense-mediated decay controls the reactivation of the oncogenic herpesviruses EBV and KSHV
The <i>BRCA1</i> Pseudogene Negatively Regulates Antitumor Responses through Inhibition of Innate Immune Defense Mechanisms
RIG-I-like receptors: their regulation and roles in RNA sensing
Dysregulation of type I interferon responses in COVID-19
Distinct and Orchestrated Functions of RNA Sensors in Innate Immunity
The antiviral activities of TRIM proteins
Zika Virus NS3 Mimics a Cellular 14-3-3-Binding Motif to Antagonize RIG-I- and MDA5-Mediated Innate Immunity
Evasion of Innate and Intrinsic Antiviral Pathways by the Zika Virus
Endogenous Nucleic Acid Recognition by RIG-I-Like Receptors and cGAS
Disassembly of the TRIM23-TBK1 Complex by the Us11 Protein of Herpes Simplex Virus 1 Impairs Autophagy
TRIM Proteins and Their Roles in Antiviral Host Defenses
TRIM25 Binds RNA to Modulate Cellular Anti-viral Defense
Centrosomal protein TRIM43 restricts herpesvirus infection by regulating nuclear lamina integrity
TRIM proteins: New players in virus-induced autophagy
Viral unmasking of cellular 5S rRNA pseudogene transcripts induces RIG-I-mediated immunity
TRIM23 mediates virus-induced autophagy via activation of TBK1
The Human Papillomavirus E6 Oncoprotein Targets USP15 and TRIM25 To Suppress RIG-I-Mediated Innate Immune Signaling