Area of research
Oncology · Molecular Biology
Research interest
Research interests include Ubiquitin and proteasome pathways, Cancer Immunotherapy and Biomarkers, Radiomics and Machine Learning in Medical Imaging, and AI in cancer detection.
Molecular classification and biomarkers of outcome with immunotherapy in extensive-stage small-cell lung cancer: analyses of the CASPIAN phase 3 study
Activation of gp130 signaling in T cells drives T <sub>H</sub> 17-mediated multi-organ autoimmunity
Actionable loss of SLF2 drives B‐cell lymphomagenesis and impairs the DNA damage response
Activated SUMOylation restricts MHC class I antigen presentation to confer immune evasion in cancer
NOXA expression drives synthetic lethality to RUNX1 inhibition in pancreatic cancer
Genetic alterations of the SUMO isopeptidase SENP6 drive lymphomagenesis and genetic instability in diffuse large B-cell lymphoma
SUMOylation inhibition overcomes proteasome inhibitor resistance in multiple myeloma
Small-molecule SUMO inhibition for biomarker-informed B-cell lymphoma therapy
CXCR4 hyperactivation cooperates with TCL1 in CLL development and aggressiveness
MCT1 is a predictive marker for lenalidomide maintenance therapy in multiple myeloma
NOXA expression drives synthetic lethality to RUNX1 inhibition in pancreatic cancer
SUMO pathway inhibition targets an aggressive pancreatic cancer subtype
The SUMO pathway in pancreatic cancer: insights and inhibition
Ubiquitination and Ubiquitin-Like Modifications in Multiple Myeloma: Biology and Therapy
Authentication of Primary Murine Cell Lines by a Microfluidics-Based Lab-On-Chip System
The SUMO Isopeptidase SENP6 Functions as a Rheostat of Chromatin Residency in Genome Maintenance and Chromosome Dynamics
PiggyBac transposon tools for recessive screening identify B-cell lymphoma drivers in mice
Age-Related Gliosis Promotes Central Nervous System Lymphoma through CCL19-Mediated Tumor Cell Retention
Activated gp130 signaling selectively targets B cell differentiation to induce mature lymphoma and plasmacytoma
Characterization of retroviral vector derived DNA-isoforms by PCR and sequencing
REGGAE: a novel approach for the identification of key transcriptional regulators
Pathogenesis and therapeutic targeting of aberrant <scp>MYC</scp> expression in haematological cancers
Targeted positron emission tomography imaging of CXCR4 expression in patients with acute myeloid leukemia
The Protein Targeting Factor Get3 Functions as ATP-Independent Chaperone under Oxidative Stress Conditions