Area of research
Epidemiology · Oncology
Research interest
Research interests include Liver Disease Diagnosis and Treatment, Cytokine Signaling Pathways and Interactions, and NF-κB Signaling Pathways.
ARID1A mutations protect follicular lymphoma from FAS-dependent immune surveillance by reducing RUNX3/ETS1-driven FAS-expression
Mast cells modulate macrophage biology through release of prestored CSF1
Genome-scale pan-cancer interrogation of lncRNA dependencies using CasRx
NF-κB subunits RelA and c-Rel selectively control CD4+ T cell function in multiple sclerosis and cancer
Hyperreactive B cells instruct their elimination by T cells to curb autoinflammation and lymphomagenesis
Analysis of the Secretome of Primary CLL Cells in Different in Vitro Co-Culture Systems
Context-Specific Determinants of the Immunosuppressive Tumor Microenvironment in Pancreatic Cancer
Slow integrin-dependent migration organizes networks of tissue-resident mast cells
An integrated cellular and molecular model of gastric neuroendocrine cancer evolution highlights therapeutic targets
In vivo interrogation of regulatory genomes reveals extensive quasi-insufficiency in cancer evolution
Lysosomal Membrane Permeabilization Sensitizes Ctss-Hyperactive Tumors to BCL2-Targeting Therapies
Selective multi-kinase inhibition sensitizes mesenchymal pancreatic cancer to immune checkpoint blockade by remodeling the tumor microenvironment
Neutrophil “plucking” on megakaryocytes drives platelet production and boosts cardiovascular disease
NF-κB in control of regulatory T cell development, identity, and function
PARP14 is a novel target in STAT6 mutant follicular lymphoma
CRISPR somatic genome engineering and cancer modeling in the mouse pancreas and liver
AP1/Fra1 confers resistance to MAPK cascade inhibition in pancreatic cancer
NIK/MAP3K14 in hepatocytes orchestrates NASH to hepatocellular carcinoma progression via JAK2/STAT5 inhibition
Notch2-mediated plasticity between marginal zone and follicular B cells
Brief homogeneous TCR signals instruct common iNKT progenitors whose effector diversification is characterized by subsequent cytokine signaling
In vivo inducible reverse genetics in patients’ tumors to identify individual therapeutic targets
Genetic Screens Identify a Context-Specific PI3K/p27Kip1 Node Driving Extrahepatic Biliary Cancer
Cathepsin S Alterations Induce a Tumor-Promoting Immune Microenvironment in Follicular Lymphoma
Stromal cell protein kinase C-β inhibition enhances chemosensitivity in B cell malignancies and overcomes drug resistance
c-Rel gain in B cells drives germinal center reactions and autoantibody production
Single-Cell Transcriptomics Identifies the Adaptation of Scart1+ Vγ6+ T Cells to Skin Residency as Activated Effector Cells
PiggyBac transposon tools for recessive screening identify B-cell lymphoma drivers in mice
The Unsolved Puzzle of c-Rel in B Cell Lymphoma
Chronic CD30 signaling in B cells results in lymphomagenesis by driving the expansion of plasmablasts and B1 cells
Aberrant Cathepsin S Induces a Supportive Immune Microenvironment in Follicular Lymphoma