Area of research
Molecular Biology · Oncology
Research interest
Research interests include Epigenetics and DNA Methylation, Histone Deacetylase Inhibitors Research, Pancreatic and Hepatic Oncology Research, and Advanced Breast Cancer Therapies.
ATM Deficiency Induces TGF-β-Mediated Stromal Programming in Pancreatic Cancer.
Activation of RAS/MEK/ERK signalling drives biliary differentiation in primary liver cancer
A liver immune rheostat regulates CD8 T cell immunity in chronic HBV infection
Genome-scale pan-cancer interrogation of lncRNA dependencies using CasRx
Heterogeneity-driven phenotypic plasticity and treatment response in branched-organoid models of pancreatic ductal adenocarcinoma
Hyperreactive B cells instruct their elimination by T cells to curb autoinflammation and lymphomagenesis
Corrigendum to “A novel Cereblon E3 ligase modulator with antitumor activity in gastrointestinal cancer” [Bioorgan. Chem. 119 (2022) 105505]
FBXL6 is a vulnerability in AML and unmasks proteolytic cleavage as a major experimental pitfall in myeloid cells
Mutual regulation of CD4+ T cells and intravascular fibrin in infections
Proteogenomic analysis reveals RNA as a source for tumor-agnostic neoantigen identification
Non-canonical functions of SNAIL drive context-specific cancer progression
An integrated cellular and molecular model of gastric neuroendocrine cancer evolution highlights therapeutic targets
Negative feedback regulation of MAPK signaling is an important driver of chronic lymphocytic leukemia progression
Targeting nucleic acid sensors in tumor cells to reprogram biogenesis and RNA cargo of extracellular vesicles for T cell-mediated cancer immunotherapy
In vivo interrogation of regulatory genomes reveals extensive quasi-insufficiency in cancer evolution
Genetic alterations of the SUMO isopeptidase SENP6 drive lymphomagenesis and genetic instability in diffuse large B-cell lymphoma
The OTUD6B‐LIN28B‐MYC axis determines the proliferative state in multiple myeloma
IL-24 intrinsically regulates Th17 cell pathogenicity in mice.
Osteoprogenitor SFRP1 prevents exhaustion of hematopoietic stem cells via PP2A-PR72/130-mediated regulation of p300
Author Correction: Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer
Proteogenomic analysis reveals RNA as an important source for tumor-agnostic neoantigen identification correlating with T-cell infiltration
NASH limits anti-tumour surveillance in immunotherapy-treated HCC
Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV
Modeling plasticity and dysplasia of pancreatic ductal organoids derived from human pluripotent stem cells.
Targeted PI3K/AKT-hyperactivation induces cell death in chronic lymphocytic leukemia
HDAC2 Facilitates Pancreatic Cancer Metastasis
XIAP restrains TNF-driven intestinal inflammation and dysbiosis by promoting innate immune responses of Paneth and dendritic cells
AGR2-Dependent Nuclear Import of RNA Polymerase II Constitutes a Specific Target of Pancreatic Ductal Adenocarcinoma in the Context of Wild-Type p53
Notch2-mediated plasticity between marginal zone and follicular B cells
Brief homogeneous TCR signals instruct common iNKT progenitors whose effector diversification is characterized by subsequent cytokine signaling