Area of research
Immunology · Oncology
Research interest
Research interests include T-cell and B-cell Immunology, Immune Cell Function and Interaction, CAR-T cell therapy research, and Immunotherapy and Immune Responses.
Metabolic quiescence of naive-like memory T cells precedes and maintains antigen-specific T cell memory
Next-generation T cell immunotherapies engineered with CRISPR base and prime editing: challenges and opportunities
PGE2 limits effector expansion of tumour-infiltrating stem-like CD8+ T cells
Bacteria and bacteriophage consortia are associated with protective intestinal metabolites in patients receiving stem cell transplantation
CD20-bispecific antibodies improve response to CD19-CAR T cells in lymphoma in vitro and CLL in vivo models
High-resolution profile of neoantigen-specific TCR activation links moderate stimulation to increased resilience of engineered TCR-T cells
Multimodal immune cell phenotyping in GI biopsies reveals microbiome-related T cell modulations in human GvHD
Genome-wide screening reveals the genetic basis of mammalian embryonic eye development
CD33-TIM3 Dual CAR T Cells: Enhancing Specificity While Maintaining Efficacy Against AML
Unique roles of co-receptor-bound LCK in helper and cytotoxic T cells
T Cells Directed against the Metastatic Driver Chondromodulin-1 in Ewing Sarcoma: Comparative Engineering with CRISPR/Cas9 vs. Retroviral Gene Transfer for Adoptive Transfer
High-resolution profiling of neoantigen-specific T cell receptor activation signatures links moderate stimulation patterns to resilience and sustained tumor control
Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition)
Fate mapping of single NK cells identifies a type 1 innate lymphoid-like lineage that bridges innate and adaptive recognition of viral infection
COVID-19 in Patients Receiving CD20-depleting Immunochemotherapy for B-cell Lymphoma
Mucosal-Associated Invariant T (MAIT) Cells Are Highly Activated and Functionally Impaired in COVID-19 Patients
Augmenting anti-CD19 and anti-CD22 CAR T-cell function using PD-1-CD28 checkpoint fusion proteins
Functional analysis of peripheral and intratumoral neoantigen-specific TCRs identified in a patient with melanoma
IFN-Gamma Producing Regulatory T Cells Counterbalance T Cell-Mediated Injury to the Intestinal Stem Cell Compartment in Mice and Humans
Spatial and temporal plasticity of neoantigen-specific T-cell responses bases on characteristics associated to antigen and TCR
Endogenous TCR promotes in vivo persistence of CD19-CAR-T cells compared to a CRISPR/Cas9-mediated TCR knockout CAR
Reverse TCR repertoire evolution toward dominant low-affinity clones during chronic CMV infection
Gut Microbiota-Derived Propionate Regulates the Expression of Reg3 Mucosal Lectins and Ameliorates Experimental Colitis in Mice
Early emergence of T central memory precursors programs clonal dominance during chronic viral infection
MHC Class I-Restricted TCR-Transgenic CD4+ T Cells Against STEAP1 Mediate Local Tumor Control of Ewing Sarcoma In Vivo
Physiological relevance of the neuronal isoform of inositol-1,4,5-trisphosphate 3-kinases in mice
A diagnostic algorithm for detection of urinary tract infections in hospitalized patients with bacteriuria: The “Triple F” approach supported by Procalcitonin and paired blood and urine cultures
Abstract PR05: T-cell receptor (TCR)-based immunotherapy in pediatric malignancy: Addressing the challenge of early metastasis and low immunogenicity
Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)
Orthotopic replacement of T-cell receptor α- and β-chains with preservation of near-physiological T-cell function