Area of research
Pulmonary and Respiratory Medicine · Genetics
Research interest
Research interests include Sarcoma Diagnosis and Treatment, Virus-based gene therapy research, CAR-T cell therapy research, and Cancer Research and Treatments.
Oncogenic ETS fusions promote DNA damage and proinflammatory responses via pericentromeric RNAs in extracellular vesicles
A costimulatory chimeric antigen receptor targeting TROP2 enhances the cytotoxicity of NK cells expressing a T cell receptor reactive to human papillomavirus type 16 E7
Zoledronic Acid Add-on Therapy for Standard-Risk Ewing Sarcoma Patients in the Ewing 2008R1 Trial
Current State of Immunotherapy and Mechanisms of Immune Evasion in Ewing Sarcoma and Osteosarcoma
T Cells Directed against the Metastatic Driver Chondromodulin-1 in Ewing Sarcoma: Comparative Engineering with CRISPR/Cas9 vs. Retroviral Gene Transfer for Adoptive Transfer
Correction to: Class I histone deacetylases (HDAC) critically contribute to Ewing sarcoma pathogenesis
Class I histone deacetylases (HDAC) critically contribute to Ewing sarcoma pathogenesis
Ewing Sarcoma-Derived Extracellular Vesicles Impair Dendritic Cell Maturation and Function
DNA methylation-based classifier and gene expression signatures detect BRCAness in osteosarcoma
Monocyte Maturation Mediators Upregulate CD83, ICAM-1 and MHC Class 1 Expression on Ewing’s Sarcoma, Enhancing T Cell Cytotoxicity
Sarcoma treatment in the era of molecular medicine
Combined Inhibition of Epigenetic Readers and Transcription Initiation Targets the EWS-ETS Transcriptional Program in Ewing Sarcoma
MHC Class I-Restricted TCR-Transgenic CD4+ T Cells Against STEAP1 Mediate Local Tumor Control of Ewing Sarcoma In Vivo
Warnsignale für Krebserkrankungen im Kindesalter
MondoA Drives Malignancy in cALL through Enhanced Adaptation to Metabolic Stress
Abstract PR05: T-cell receptor (TCR)-based immunotherapy in pediatric malignancy: Addressing the challenge of early metastasis and low immunogenicity
Genotyping circulating tumor DNA of pediatric Hodgkin lymphoma
Community-driven development of a modified progression-free survival ratio for precision oncology
Exosomes transmit retroelement RNAs to drive inflammation and immunosuppression in Ewing Sarcoma
Unusual Course of a Diffuse Midline Glioma Exhibits Upcoming Therapeutic Options through Novel Molecular Genetic Analyses
The landscape of genomic alterations across childhood cancers
Author Correction: The landscape of genomic alterations across childhood cancers
Transcriptome based individualized therapy of refractory pediatric sarcomas: feasibility, tolerability and efficacy
Donor lymphocyte infusions in adolescents and young adults for control of advanced pediatric sarcoma
Pappalysin-1 T cell receptor transgenic allo-restricted T cells kill Ewing sarcoma<i>in vitro</i>and<i>in vivo</i>
Ewing sarcoma partial regression without GvHD by chondromodulin-I/HLA-A*02:01-specific allorestricted T cell receptor transgenic T cells
Human HLA-A*02:01/CHM1+ allo-restricted T cell receptor transgenic CD8+ T Cells specifically inhibit Ewing sarcoma growth<i>in vitro</i>and<i>in vivo</i>
Lysosome-associated membrane glycoprotein 1 predicts fratricide amongst T cell receptor transgenic CD8+ T cells directed against tumor-associated antigens
Abstract 2462: MondoA mediates <i>in vivo</i> aggressiveness of common ALL and may serve as a T-cell immunotherapy target
Abstract 3202: Transgenic antigen-specific, HLA-A*02:01-allo-restricted cytotoxic T cells recognize tumor-associated target antigen STEAP1 with high specificity