Area of research
Pulmonary and Respiratory Medicine · Oncology
Research interest
Research interests include Sarcoma Diagnosis and Treatment, CAR-T cell therapy research, Cancer, Hypoxia, and Metabolism, and Glioma Diagnosis and Treatment.
High-resolution proteomic analysis of medulloblastoma clinical samples identifies therapy-resistant subgroups and MYC immunohistochemistry as a powerful outcome predictor
Engineered CD47 protects T cells for enhanced antitumour immunity
Early rhombic lip Protogenin+ve stem cells in a human-specific neurovascular niche initiate and maintain group 3 medulloblastoma
Oncogenic ETS fusions promote DNA damage and proinflammatory responses via pericentromeric RNAs in extracellular vesicles
323 Development of nuclear envelope protein-targeting CAR T cells for treatment of hyperproliferative<i>MYC</i>-driven group 3 medulloblastoma
Preclinical development of a chimeric antigen receptor T cell therapy targeting FGFR4 in rhabdomyosarcoma
Transcriptional immunogenomic analysis reveals distinct immunological clusters in paediatric nervous system tumours
Anti-GD2 synergizes with CD47 blockade to mediate tumor eradication
Characterization of a small molecule inhibitor of disulfide reductases that induces oxidative stress and lethality in lung cancer cells
Transcriptional immunogenomic analysis reveals distinct immunological clusters in pediatric nervous system tumours
GPC2-CAR T cells tuned for low antigen density mediate potent activity against neuroblastoma without toxicity
Global analysis of shared T cell specificities in human non-small cell lung cancer enables HLA inference and antigen discovery
NOT-Gated CD93 CAR T Cells Effectively Target AML with Minimized Endothelial Cross-Reactivity
Ewing Sarcoma-Derived Extracellular Vesicles Impair Dendritic Cell Maturation and Function
EMBR-21. CLINICALLY TRACTABLE OUTCOME PREDICTION OF GROUP 3/4 MEDULLOBLASTOMA BASED ON TPD52 IMMUNOHISTOCHEMISTRY: A MULTICOHORT STUDY
Locoregionally administered B7-H3-targeted CAR T cells for treatment of atypical teratoid/rhabdoid tumors
Locoregional delivery of CAR T cells to the cerebrospinal fluid for treatment of metastatic medulloblastoma and ependymoma
Metabolic Regulation of the Epigenome Drives Lethal Infantile Ependymoma
MondoA Drives Malignancy in cALL through Enhanced Adaptation to Metabolic Stress
Shared Expression of CD93 and Other Antigens By AML and Endothelial Cells Highlights a Need for Rational Combinatorial Targeting
CAR T Cells Targeting B7-H3, a Pan-Cancer Antigen, Demonstrate Potent Preclinical Activity Against Pediatric Solid Tumors and Brain Tumors
Provocative questions in osteosarcoma basic and translational biology: A report from the Children's Oncology Group
Exosomes transmit retroelement RNAs to drive inflammation and immunosuppression in Ewing Sarcoma
Single-pot, solid-phase-enhanced sample preparation for proteomics experiments
A Hematogenous Route for Medulloblastoma Leptomeningeal Metastases
MBRS-57. TARGETING METABOLIC ADAPTATION IN MYC/MYCN AMPLIFIED PEDIATRIC MEDULLOBLASTOMA AND NEUROBLASTOMA
CBMT-05. ROLE OF THE let7-eEF2K AXIS IN MYC-DRIVEN MEDULLOBLASTOMA ADAPTATION TO NUTRIENT DEPRIVATION
TEM8/ANTXR1-Specific CAR T Cells as a Targeted Therapy for Triple-Negative Breast Cancer
MYCN amplified neuroblastoma requires the mRNA translation regulator eEF2 kinase to adapt to nutrient deprivation