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Mania Ackermann

Medizinische Hochschule Hannover · DE
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Area of research
Molecular Biology · Pulmonary and Respiratory Medicine
Research interest
Research interests include Biology, Induced pluripotent stem cell, Haematopoiesis, Immunology, Pulmonary alveolar proteinosis, and Cell biology.
h-index
citations
1,768
works
26
NIH funding
primary concept
email

Recent publications

FLT3L governs the development of partially overlapping hematopoietic lineages in humans and mice
Cell 2024cited by 53position: middledoi
Standardized generation of human iPSC-derived hematopoietic organoids and macrophages utilizing a benchtop bioreactor platform under fully defined conditions
Stem Cell Research & Therapy 2024cited by 16position: firstdoi
Scalable generation of functional human iPSC-derived CAR-macrophages that efficiently eradicate CD19-positive leukemia
Journal for ImmunoTherapy of Cancer 2023cited by 62position: middledoi
Continuous human iPSC-macrophage mass production by suspension culture in stirred tank bioreactors
Nature Protocols 2022cited by 116position: firstdoi
Beyond “Big Eaters”: The Versatile Role of Alveolar Macrophages in Health and Disease
International Journal of Molecular Sciences 2021cited by 40position: middledoi
Human iPSC-derived macrophages for efficient<i>Staphylococcus aureus</i>clearance in a murine pulmonary infection model
Blood Advances 2021cited by 32position: middledoi
Restored Macrophage Function Ameliorates Disease Pathophysiology in a Mouse Model for IL10 Receptor-deficient Very Early Onset Inflammatory Bowel Disease
Journal of Crohn s and Colitis 2021cited by 22position: firstdoi
A 3D iPSC-differentiation model identifies interleukin-3 as a regulator of early human hematopoietic specification
Haematologica 2020cited by 41position: firstdoi
Human Lentiviral Gene Therapy Restores the Cellular Phenotype of Autosomal Recessive Complete IFN-γR1 Deficiency
Molecular Therapy — Methods & Clinical Development 2020cited by 17position: middledoi
Enhanced Ex Vivo Generation of Erythroid Cells from Human Induced Pluripotent Stem Cells in a Simplified Cell Culture System with Low Cytokine Support
Stem Cells and Development 2019cited by 81position: middledoi
Bioreactor-based mass production of human iPSC-derived macrophages enables immunotherapies against bacterial airway infections
Nature Communications 2018cited by 162position: firstdoi
Pulmonary Transplantation of Human Induced Pluripotent Stem Cell–derived Macrophages Ameliorates Pulmonary Alveolar Proteinosis
American Journal of Respiratory and Critical Care Medicine 2018cited by 73position: middledoi
iPSC-Derived Macrophages Effectively Treat Pulmonary Alveolar Proteinosis in Csf2rb-Deficient Mice
Stem Cell Reports 2018cited by 48position: middledoi
Concise Review: Towards the Clinical Translation of Induced Pluripotent Stem Cell-Derived Blood Cells—<i>Ready for Take-Off</i>
Stem Cells Translational Medicine 2018cited by 39position: middledoi
Impaired IFNγ-Signaling and Mycobacterial Clearance in IFNγR1-Deficient Human iPSC-Derived Macrophages
Stem Cell Reports 2017cited by 33position: middledoi
TALEN-mediated functional correction of human iPSC-derived macrophages in context of hereditary pulmonary alveolar proteinosis
Scientific Reports 2017cited by 30position: middledoi
Gene correction of HAX1 reversed Kostmann disease phenotype in patient-specific induced pluripotent stem cells
Blood Advances 2017cited by 24position: middledoi
Identification and characterization of novel functional markers of EHT
Experimental Hematology 2017cited by 0position: middledoi
Large-Scale Hematopoietic Differentiation of Human Induced Pluripotent Stem Cells Provides Granulocytes or Macrophages for Cell Replacement Therapies
Stem Cell Reports 2015cited by 252position: middledoi
Lost in translation: pluripotent stem cell‐derived hematopoiesis
EMBO Molecular Medicine 2015cited by 99position: firstdoi
A minimal ubiquitous chromatin opening element (UCOE) effectively prevents silencing of juxtaposed heterologous promoters by epigenetic remodeling in multipotent and pluripotent stem cells
Nucleic Acids Research 2015cited by 90position: middledoi
TALEN-mediated functional correction of X-linked chronic granulomatous disease in patient-derived induced pluripotent stem cells
Biomaterials 2015cited by 76position: middledoi
Pulmonary transplantation of macrophage progenitors as effective and long-lasting therapy for hereditary pulmonary alveolar proteinosis
Science Translational Medicine 2014cited by 116position: middledoi
Gene Correction of Human Induced Pluripotent Stem Cells Repairs the Cellular Phenotype in Pulmonary Alveolar Proteinosis
American Journal of Respiratory and Critical Care Medicine 2013cited by 100position: middledoi
A ubiquitous chromatin opening element prevents transgene silencing in pluripotent stem cells and their differentiated progeny
Stem Cells 2013cited by 82position: middledoi
Promoter and lineage independent anti-silencing activity of the A2 ubiquitous chromatin opening element for optimized human pluripotent stem cell-based gene therapy
Biomaterials 2013cited by 64position: firstdoi

Grants

No grants ingested yet.

Frequent collaborators

Nico Lachmann · Medizinische Hochschule Hannover25 papers (2013–2024)Thomas Moritz · Medizinische Hochschule Hannover12 papers (2013–2023)Axel Schambach · Medizinische Hochschule Hannover10 papers (2013–2023)Adele Mucci · Medizinische Hochschule Hannover7 papers (2013–2021)Christine Happle · Medizinische Hochschule Hannover7 papers (2013–2018)Miriam Hetzel · Medizinische Hochschule Hannover7 papers (2013–2021)Gesine Hansen · German Center for Infection Research7 papers (2013–2023)Kathrin Haake · Medizinische Hochschule Hannover5 papers (2017–2020)Gudrun Göhring · Epigenomics (Germany)5 papers (2013–2018)Tobias Cantz · Medizinische Hochschule Hannover4 papers (2013–2017)Robert Zweigerdt · Medizinische Hochschule Hannover4 papers (2013–2022)Sebastian Brennig · Medizinische Hochschule Hannover4 papers (2013–2018)Anna Rafiei Hashtchin · Medizinische Hochschule Hannover4 papers (2018–2024)Henning Kempf · Medizinische Hochschule Hannover4 papers (2018–2022)Mark Kühnel · Medizinische Hochschule Hannover4 papers (2015–2020)Silke Glage · Medizinische Hochschule Hannover4 papers (2018–2021)Markus Abeln · Medizinische Hochschule Hannover3 papers (2020–2024)Christian Brendel · Harvard Stem Cell Institute3 papers (2013–2021)Sylvia Merkert · Medizinische Hochschule Hannover3 papers (2013–2020)Danny Jonigk · Medizinische Hochschule Hannover3 papers (2017–2020)
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