Area of research
Oncology · Genetics
Research interest
Research interests include Pancreatic and Hepatic Oncology Research, Glioma Diagnosis and Treatment, Cancer Immunotherapy and Biomarkers, and Cancer Research and Treatments.
XL888 and pembrolizumab modulate the immune landscape of colorectal tumors in a phase Ib/II clinical trial
High-Dimensional Protein Analysis Uncovers Distinct Immunologic and Stromal Features in Primary and Metastatic Pancreatic Ductal Adenocarcinoma
Mechanism of enhancing chemotherapy efficacy in pancreatic ductal adenocarcinoma with paricalcitol and hydroxychloroquine
A paracrine circuit of IL-1β/IL-1R1 between myeloid and tumor cells drives genotype-dependent glioblastoma progression
Time-resolved live-cell spectroscopy reveals EphA2 multimeric assembly
Dual IL-6 and CTLA-4 blockade regresses pancreatic tumors in a T cell– and CXCR3-dependent manner
Anti-EGFR Antibodies in the Management of Advanced Colorectal Cancer
The tumor microenvironment in pancreatic ductal adenocarcinoma: current perspectives and future directions
A multi-center, single-arm, phase Ib study of pembrolizumab (MK-3475) in combination with chemotherapy for patients with advanced colorectal cancer: HCRN GI14-186
Platelet-derived growth factor beta is a potent inflammatory driver in paediatric high-grade glioma
Genetic driver mutations introduced in identical cell‐of‐origin in murine glioblastoma reveal distinct immune landscapes but similar response to checkpoint blockade
IDH1-R132H acts as a tumor suppressor in glioma via epigenetic up-regulation of the DNA damage response
Human Mesenchymal glioblastomas are characterized by an increased immune cell presence compared to Proneural and Classical tumors
Tumour-associated macrophages exhibit anti-tumoural properties in Sonic Hedgehog medulloblastoma
Tumour-associated macrophage-derived interleukin-1 mediates glioblastoma-associated cerebral oedema
Chromodomain Helicase DNA-Binding Protein 7 Is Suppressed in the Perinecrotic/Ischemic Microenvironment and Is a Novel Regulator of Glioblastoma Angiogenesis
Cellular and Molecular Identity of Tumor-Associated Macrophages in Glioblastoma
Macropinocytosis of Bevacizumab by Glioblastoma Cells in the Perivascular Niche Affects their Survival