Area of research
Genetics · Immunology
Research interest
Research interests include Glioma Diagnosis and Treatment, Immune cells in cancer, Neuroinflammation and Neurodegeneration Mechanisms, and Cancer, Hypoxia, and Metabolism.
An early precursor CD8+ T cell that adapts to acute or chronic viral infection
A paracrine circuit of IL-1β/IL-1R1 between myeloid and tumor cells drives genotype-dependent glioblastoma progression
Monocyte depletion enhances neutrophil influx and proneural to mesenchymal transition in glioblastoma
PD-1 combination therapy with IL-2 modifies CD8+ T cell exhaustion program
Necrotic reshaping of the glioma microenvironment drives disease progression
Spatially targeted brain cancer immunotherapy with closed-loop controlled focused ultrasound and immune checkpoint blockade
Genetic driver mutations introduced in identical cell‐of‐origin in murine glioblastoma reveal distinct immune landscapes but similar response to checkpoint blockade
IDH1-R132H acts as a tumor suppressor in glioma via epigenetic up-regulation of the DNA damage response
Human Mesenchymal glioblastomas are characterized by an increased immune cell presence compared to Proneural and Classical tumors
Intravital 2-photon imaging reveals distinct morphology and infiltrative properties of glioblastoma-associated macrophages
Perinodal Adipose Tissue Participates in Immune Protection through a Lymphatic Vessel–Independent Route
<scp>TRIM</scp>8 regulates stemness in glioblastoma through <scp>PIAS</scp>3‐<scp>STAT</scp>3
5-Aminolevulinic Acid Guided Sampling of Glioblastoma Microenvironments Identifies Pro-Survival Signaling at Infiltrative Margins