Area of research
Molecular Biology · Epidemiology
Research interest
Research interests include Cell biology, Endoplasmic reticulum, Mitochondrion, Biology, Connexin, and Autophagy.
The BCL2 family: from apoptosis mechanisms to new advances in targeted therapy
Endoplasmic reticulum–mitochondria contacts are prime hotspots of phospholipid peroxidation driving ferroptosis
Aspartate signalling drives lung metastasis via alternative translation
ER calcium depletion as a key driver for impaired ER-to-mitochondria calcium transfer and mitochondrial dysfunction in Wolfram syndrome
A deep phenotyping study in mouse and iPSC models to understand the role of oligodendroglia in optic neuropathy in Wolfram syndrome
The ER-mitochondria interface, where Ca2+ and cell death meet
Connexin hemichannels as candidate targets for cardioprotective and anti-arrhythmic treatments
Pore-forming proteins as drivers of membrane permeabilization in cell death pathways
Long-term culture of patient-derived cardiac organoids recapitulated Duchenne muscular dystrophy cardiomyopathy and disease progression
TMBIM5 loss of function alters mitochondrial matrix ion homeostasis and causes a skeletal myopathy
Balancing ER-Mitochondrial Ca2+ Fluxes in Health and Disease
Cx43 hemichannel microdomain signaling at the intercalated disc enhances cardiac excitability
The role of Bcl-2 proteins in modulating neuronal Ca2+ signaling in health and in Alzheimer's disease
Bcl-xL acts as an inhibitor of IP3R channels, thereby antagonizing Ca2+-driven apoptosis
A comprehensive overview of the complex world of the endo- and sarcoplasmic reticulum Ca2+-leak channels
SOX9-induced Generation of Functional Astrocytes Supporting Neuronal Maturation in an All-human System
Necroptosis in Immuno-Oncology and Cancer Immunotherapy
APOL1 C-Terminal Variants May Trigger Kidney Disease through Interference with APOL3 Control of Actomyosin
Cx43 channels and signaling via IP3/Ca2+, ATP, and ROS/NO propagate radiation-induced DNA damage to non-irradiated brain microvascular endothelial cells
Small molecule 3PO inhibits glycolysis but does not bind to 6‐phosphofructo‐2‐kinase/fructose‐2,6‐bisphosphatase‐3 (PFKFB3)
Transmembrane BAX Inhibitor-1 Motif Containing Protein 5 (TMBIM5) Sustains Mitochondrial Structure, Shape, and Function by Impacting the Mitochondrial Protein Synthesis Machinery
HIF-1α metabolically controls collagen synthesis and modification in chondrocytes
Non-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics
Interaction of α Carboxyl Terminus 1 Peptide With the Connexin 43 Carboxyl Terminus Preserves Left Ventricular Function After Ischemia‐Reperfusion Injury
Bcl-2 and IP3 compete for the ligand-binding domain of IP3Rs modulating Ca2+ signaling output
Type 3 IP3 receptors driving oncogenesis
Emerging molecular mechanisms in chemotherapy: Ca2+ signaling at the mitochondria-associated endoplasmic reticulum membranes
Role of Mitochondria-Associated ER Membranes in Calcium Regulation in Cancer-Specific Settings
Constitutive IP3 signaling underlies the sensitivity of B-cell cancers to the Bcl-2/IP3 receptor disruptor BIRD-2
Deleterious effects of calcium indicators within cells; an inconvenient truth